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drug discovery and future medicines

This class was created by Brainscape user Hibou El-Bizri. Visit their profile to learn more about the creator.

By: Hibou El-Bizri
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Decks in this class (21)

Intro to drug discovery
Routes of drug discovery,
When are efficacy pk and toxicolo...,
Principle assays of early drug di...
8  cards
target identification and validation and lead optimisation
What makes a good pharmacological...,
Purpose of target identification ...,
Lead identification and methods
6  cards
Pre-clinical evaluation and marketing authorisation
What is preclinical evaluation,
Selectivity and off target effects,
Toxicology testing
8  cards
Intro to biologics
What are biologics,
Advantages of protein therapeutics,
Disadvantages of protein therapeu...
6  cards
intro to autoimmune diseases and rhuematoid arthritis
Development of autoimmune diseases,
Examples of autoimmune diseases,
Osteoarthritis cause pathophysiol...
5  cards
Immunosuppressants
What are dmards,
Methotrexate,
Azathioprine
9  cards
Biologics in autoimmune diseases
Anti tnfa therapies,
Targeting of il 6,
Abatacept
6  cards
PK of biologics
Absorption,
Distribution,
Elimination
5  cards
Hypercholestrolaemia
What is hypercholesterolaemia and...,
Statins mechanism,
Pcsk9
6  cards
Heart failure
What is heart failure and what ar...,
Chronic heart failure diagnosis a...,
Targeting the raas
12  cards
Preclinical pharmacokinetics
Purpose of preclinical pk,
Log p,
Molecular weight
9  cards
Clinical pharmacokinetics
First in human studies,
Mabel,
End points and analysis of phase ...
16  cards
Modelling approaches in pharmacokinetics
Pop pk,
Types of variability,
Mixed effect modelling
4  cards
Pharmacogenetics and personalised medicines
What is pharmacogenetics and phar...,
Single nucleotide polymorphisms,
Copy number variation
12  cards
Novel inhibitors of cell proliferation
Pi3k pathway in cancer,
Drugs targeting the pi3k pathway,
Kras in cancer
5  cards
Biologics in cancer
Her2 in cancer and targeting it,
What are nano bodies and example,
Immune system in cancer treatment...
5  cards
Kidney structure and function
Roles of the kidney,
Anatomy of kidney,
Nephron anatomy
5  cards
Renal diseases and pharmacokinetics
Kidney diseases and its progression,
Aki,
Ckd
6  cards
Advances in asthma and COPD
Asthma and copd pathology,
Mabs for asthma,
Bitter taste receptor agonists
7  cards
Cystic fibrosis and cough
What is cystic fibrosis and aims ...,
Cftr modulators,
What is cough and what drives it
5  cards
Advances in therapeutics for neurodegeneration
Prevalence and drug discovery lim...,
Molecular and tissue pathology,
Pathology of als
7  cards

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drug discovery and future medicines

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