This class was created by Brainscape user Emma Schram. Visit their profile to learn more about the creator.
By:
Emma Schram
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Decks in this class (11)
Lecture 1 ‘The genomic basis for the evolution of human traits’
Encephalization quotient eq or en...,
Most dramatically changed part of...,
Expansion of the mouse neuronal p...
8
cards
Lecture 2 ‘Cross species conservation and variation’
Pseudogene insertion expression,
Ultraconserved elements uce,
Human accelerated regions hars
10
cards
Lecture 3 'Human-specific duplicated genes and their role in human brain development and disease'
How can we accumulate how long ag...,
Segmental duplications,
Core duplications
10
cards
lecture 4 'segmental duplications as source for genomic innovation: The case of NOTCH2NL'
Notch signalling,
The notch2nl gene is only seen in...,
Notch2nl
6
cards
Lecture 5 'Human genetic engineering to model neurodevelopmental disorders
Main problem of using ipscs,
Neurodevelopmental disorders ndds...,
Genetic manipulation
4
cards
Lecture 6 'Archaic genomes & our genome under attack: origin of repetitive DNA elements''
Neanderthals and homo sapiens som...,
Bottleneck situation,
Interbreeding
15
cards
Lecture 7 "Our genome strikes back: The evolutionary arms race between KRAB zinc finger genes and transposable elements''
Expansion of krab zinc finger genes,
What is the purpose of having man...,
Zinc fingers
6
cards
Lecture 8 'Unraveling the genomic basis of speciation'
What is a species,
Reproductive isolation barrier ev...,
Hotspot paradox
8
cards
Lecture 10 'Tandem repeats & repeat expansion disorders'
What are tandem repeats,
Models which can lead to expantion,
How to study strs
11
cards
Lecture 11 'SVAs and their contribution to human disease'
Non autonomous,
Human polymorphic svas,
Definition and structure of sva
8
cards
Lecture 12 ‘SV-SVAs as hidden neuronal gene regulators in health and disease’
Heritability,
Linkage disequilibrium ld
2
cards
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HGBE
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