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Jocasta Cochrane
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Decks in this class (16)
1. Infectious Diseases in the 21st Century
1. To describe the change in bacterial infectious diseases in recent years with specific examples 2. To explain drivers for the change in bacteria infectious diseases in the community and hospital and to consider antibiotic resistance
49
cards
2. The Evolution of Antibiotic Resistance
1. To explain how minimum inhibitory concentration of an antibiotic is linked with the definition of antibiotic resistant.
2. To described, with appropriate examples, the various strategies that bacteria use for antibiotic resistance.
3. To explain the rise of ß-lactam resistance in Gram-negative and Gram-positive bacteria with reference to the mobile genetic elements and recombination mechanisms primarily involved.
54
cards
3. The As, Bs, Cs and Ds of beta-lactamases
1. Describe ß-lactam antibiotics and how they work
2. Explain how PBPs can be modified to confer ß-lactam resistance
3. Define ß-lactamases and what they do
4. Describe the different types of ß-lactamases and how they differ
5. Give some examples of ß-lactamases
60
cards
4. Carbapenemases and ß-lactamase Inhibitors
1. Discuss how class A ß-lactamases evolve to become ESBLs.
2. Identify the most clinically important carbapenemases.
3. Describe the basis for carbapenemase activity in Class A and class B enzymes.
4. Describe the usefulness and limitations of currently available ß-lactamase inhibitors.
83
cards
5. New developments in (fluoro)quinolone Resistance
1. Describe the mechanism of action of quinolone antibiotics.
2. Describe mechanisms of quinolone resistance.
3. Discuss how different mechanisms can work together to confer resistance.
68
cards
6. Multi-drug resistant Enterbacterales as a serious nosocomial threat.
1. To describe the key enterobacterales species relevant for the community and healthcare-associated infection and the common diseases caused.
2. To link with other lectures to explain how multi-drug resistance can emerge with specific examples, including intrinsic and acquired mechanisms.
3. To particularly discuss how multiple resistance mechanisms can come together to give resistance to carbapenems and the ß-lactam/ß-lactamase inhibitor combination.
55
cards
7. One health selection and transmission of antimicrobial resistance
What is one health,
What are the most likely bacteria...,
What do other infections need to ...
49
cards
8. The rise of multi-drug resistant Non-fermenting Gram-negative bacilli
What are nfgnbs,
Why are nfgnbs important pathogens,
Why is pseudomonas aeruginosa the...
60
cards
9. Pneumonia
What is pneumonia,
How is pneumonia defined,
How does pneumonia cause fever
48
cards
10. MRAS and VRE as hospital and community pathogens
What is staphylococcus aureus,
How is mrsa specifically tested f...,
What environment is s aureus foun...
63
cards
11. Vancomycin resistance in enterococci and staphylococcus aureus
Why is vancomycin resistance a pr...,
Is s aureus gram positive or gram...,
How can you tell a bacteria is gr...
79
cards
12. Fungal infections - current challenges
Why are fungal infections under a...,
Are fungi diverse,
Why do fungi associate with plants
71
cards
13. Diagnosis, management and treatment of fungal diseases
Why is fast correct diagnosis for...,
What needs to be used alongside d...,
Why are superficial fungal infect...
116
cards
14. Methods of combating antibiotic resistance
What does antibiotic resistance d...,
What needs to be remembered about...,
Why does being in lots of contact...
69
cards
15. Infection control: bench to bedside
What are healthcare associated in...,
What impact does healthcare assoc...,
Are hcai preventable
69
cards
16. The leaky antibacterial discovery pipeline
What is the amr problem in the ri...,
What are eskape pathogens,
What are the eskape pathogens
57
cards
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Medical Microbiology
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