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orla Ruane
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Decks in this class (21)
Pharmaceutical analysis: Measurement and data reliability
What are the steps in drug analys...,
What does a representative sample...,
What is an analyte
25
cards
Introduction to drug discovery
What is a drug,
What 2 phases can drug discovery ...,
What steps are in drug discovery
25
cards
Thermodynamic basis of protein-ligand interactions
What are the most common target f...,
What targets are viewed as undrug...,
What must a drug fit into
16
cards
Thermodynamic basis of drug action
What must the drug be in in order...,
What forms can increase rate of s...,
What is thermodynamic solubility
8
cards
Mass Spectrometry
What is mass spectrometry,
What does it require the generati...,
Why is mass spectrometry useful i...
38
cards
NMR
What is the frequency of nmr,
What magnetic properties do atomi...,
What does the magnetic moment cau...
57
cards
Proton NMR chemical shift values
Alkyl proton rch3 primary,
Alkyl rch2ch3 secondary,
Alkyl c3ch tertiary
18
cards
Carbon NMR chemical shift values
Alkyl rch3,
Alkyl rch2r,
Alkyl rchr2
12
cards
EMR and UV-vis spectrophotometery
What is the electromagnetic spect...,
Name the em spectrum,
What are light waves
48
cards
IR spectroscopy
What is a wavenumber v,
Can ir energy cause electronic tr...,
Define vibrational state
53
cards
UV spec
What makes up a uv spectrophometer,
How does the spectrophotometer work,
What happens in a dual beam instr...
42
cards
Chromatographic techniques
What are the 6 different types of...,
What are the common features of a...,
What is column chromatography
28
cards
Extractions and sample preparation
What is a galenical,
What is a menstrumm,
What is a marc
32
cards
HPLC
What is hplc,
Why are the solvents used degassed,
What does the mixing valve do
26
cards
Elemental analysis
What is elemental analysis,
What are the most common types of...,
What is elemental composition the...
8
cards
Natural products as sources of drugs
Where do drugs come from,
Which drugs are chemically synthe...,
What are organic compounds isolat...
28
cards
Enzyme inhibition 1: reversible and irreversible enzyme inhibitors
What is the general concept of en...,
What does enzyme inhibition lead to,
What are the modes of inhibition
39
cards
Enzyme inhibition 2: suicide inactivators and transition state analogues
What are the 2 types of mechanism...,
What are the advantages of mechan...,
What is the mode of interaction w...
24
cards
Drug design: finding a lead
What is the lead candidate,
How is the lead candidate found,
What is teprotide
20
cards
Drug Design: Optimising binding interactions
What are lead compounds from the ...,
Why would this be needed,
What are the strategies of optimi...
25
cards
Lead optimisation in drug design
What permeability does a drug hav...,
What effect will varying alkyl su...,
What effect will masking or remov...
37
cards
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Medicine sem 1
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