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Adam Bills
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Decks in this class (17)
BOD L1 Introduction to Diabetes
Aims - To understand the cells, tissues and hormones involved in the regulation of glucose homeostasis, and how these can be controlled in the treatment and management of diabetes.
LO -
-Describe the different types of diabetes
-Describe some of the structures and chemical changes involved in glucose regulation within the body
-Explain how diabetes is diagnosed
-Describe the treatment and management of diabetes
18
cards
BOD L2 Introduction to Obesity
Understand the definition and context of obesity.
Describe models used to study obesity.
Understand how obesity contributes to chronic non-communicative diseases.
15
cards
BOD L3+4 T2 Diabetes genes and mechanisms
Aim: To link understanding of pancreatic function with type 2 diabetes pathology and treatment rationales.
LO:
-Detail the main cellular pathways of insulin secretion and islet immunomodulation.
-Provide detail of the molecular events leading to pancreatic dysfunction in type 2 diabetes, an ddetiail how diet and extracellular environment impact upon this.
-Provide detail of specific genes linked to diabetes predisposition.
34
cards
BOD L5 Ischaemic preconditioning and cardioprotection
What is ischaemia,
What happens when cells receive l...,
What are some physicological cons...
30
cards
BOD L6 Introduction to Athersclerosis
Understand basics of artery wall.
Understand appearance and development of atherosclerosis.
Theories of atherosclerosis, and links to obesity.
25
cards
BOD L7 Diabetes in CVD
Have an awareness of epidemiological studies linking type 2 diabetes and CVD.
Understand the molecular mechanisms that increase the risk of CVD in type 2 diabetics
26
cards
BOD L8 Regression, Treatment & Prevention of CVD
Appreciate the evidence for regression of atherosclerosis.
Be aware of a variety of treatments for cardiovascular disease.
Be familiar with guidelines for the prevention fo cardiovascular disease.
19
cards
BOD L9 IPC & cardioprotection pt2
How is intrisnic apoptotis initiated,
How does cytochrome c act within ...,
Which to antagonists inhibit apop...
16
cards
BOD L10 ISC & Cardioprotection pt3
What role do kinases play in ipc,
What is delayed ipc,
How does delayed ipc differ funde...
23
cards
BOD L11+12 Cancer Signalling Networks
What two ways can ecm provide sup...,
What are the three major kinds of...,
What role does autophagy play in ...
55
cards
BOD L13 Growth regulation and signal transduction
What are the six main hallmarks o...,
What is the model for gf signalling,
How is egf signalling subverted i...
42
cards
BOD L14 Stem cell biology
What are the two major properties...,
What two purposes do these proper...,
Where are totipotent stem cells f...
13
cards
BOD L15 Cancer stem cells
Aim:
Discuss the role of cancer stem cells in cancer imitation and progression.
LO:
Define what are cancer stem cells.
Define EMT.
Discuss their role in cancer
17
cards
BOD L16 Tumour progression and metastasis
Learning outcomes:
Understand the biological basis of tumour progression and metastasis.
To develop a critical awareness and understand of the cellular and molecular features of tumour progression.
Critical understanding of the importance of host-tumour interactions.
26
cards
BOD L17 Tumour angiogenesis
To discuss the steps and determinants of angiogenesis and how it relates to tumour progression & metastasis
20
cards
L18 - Tumour immunology and immunotherapy
An overview of immune response/basic immunology.
Immune response to cancer.
Tumour antigens and their identification.
Contents:
- How manipulation of immune system can help in treatment of cancer?
- Types of tumour antigens that can be targeted.
- Activation of anti-tumour T cells by immunisation with cancer antigens. Adoptive transfer.
- To identify mechanisms that limit cancer regression despite the presence of anti-tumour T cells?
- Strategies of tumour immune evasion.
17
cards
BOD L19 - Tumour Immunotherapy
To understand what cancer immunotherapy is.
To identify the main types and mechanisms of immunotherapy.
Questions:
- Can immune stimulators combat cancer?
- Which forms of immunotherapy can be used?
- Is vaccination effective against established tumours?
- Can anti-tumour responses be generated in vitro?
- Can in vitro responses translate into in vivo effects?
- What barriers are there to develop effective IT?
16
cards
More about
Biology of Disease
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