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amie briggs
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Decks in this class (26)
31st Jan
What is hyperplasia,
What is dysplasia,
How long is the average human cel...
24
cards
1st February
Within the cell cycle in which ph...,
During which phase is the cell re...,
Which cdk cyclin complexes contro...
31
cards
3rd march
What are the three main families ...,
What is the main function of mmps,
What is the main function of seri...
20
cards
24th January
What is the largest cause of deat...,
How many people in the uk will su...,
How many people survive cancer
10
cards
25th Jan
Is cancer an environmental or gen...,
How large is a tumour before it i...,
Are tumours monoclonal
11
cards
26th Jan - Hallmarks of Cancer
Which tissue did carcinomas origi...,
Which tissue do sarcomas originat...,
Which type of cancer arises from ...
27
cards
27th Jan - Properties of Cancer Cells
What percentage of human cancers ...,
Why do epithelial cells have the ...,
What are the two main components ...
28
cards
8th Feb - Discovery of Oncogenes
What is an oncogene,
Who first identified that bacteri...,
What are kochs postulates
19
cards
9th Feb - Discovery of oncogenes
What are the key oncogenes,
Who identified oncogenes in 1984 ...,
How was the src gene identified
28
cards
10th Feb - Oncogenes and Signal Transduction Pathways in Cancer
What are the three ways the signa...,
What are the common alterations o...,
Name a treatment that targets egf...
25
cards
14th Feb - WNT, NFkB, Hedgehog and notch signalling pathways
Where are notch ligands localised,
What are the notch receptors,
Outline the notch signalling pathway
22
cards
15th Feb - Intro to Tumour Suppressors and Rb
What is a tumour suppressor,
What are the three different type...,
What are gatekeepers
21
cards
16th Feb - p53
When was p53 discovered,
How was p53 identified,
How was it identified that p53 wa...
39
cards
17th Feb - The CDK2A locus, p21 and PTEN
What is the role of p16ink4,
Outline the mechanism of p16ink4s...,
Where was p16ink4 first discovere...
25
cards
21st Feb - Senescence
What is cellular senescence,
What is the hayflick limit,
What is telomere shortening
23
cards
2nd Feb - DNA Damage and Replication Stress responses
What is a mutation,
What is genetic instability,
What is microsatellite instability
39
cards
3rd Feb - Aneuploidy, CIN and Mitotic errors
What is aneuploidy,
How can aneuploidy be detected,
What is the most common genetic c...
19
cards
7th Feb - Mitotic Spindle Assembly Checkpoint
What are the cyclin cdk complexes...,
What are the kinases that regulat...,
What is the function of plk1
41
cards
1st March - Mechanisms of Tumour metastasis and angiogenesis
Outline the architecture of a tissue,
Outline the metastatic cascade,
What is intravasation
31
cards
2nd March - Role of Integrins
What are integrins,
Outline the structure of an integrin,
What is the main function of inte...
27
cards
7th March - Positive regulators of angiogenesis
What is angiogenesis,
What is vasculogenesis,
What is a chick chorioallantoic m...
36
cards
8th March - Endogenous inhibitors of angiogenesis
What was the first endogenous neg...,
What are the different effects of...,
What is the lewis lung tumour model
36
cards
9th March - Early Detection
What are the survival rates for b...,
What are the three main methods o...,
What are the two main types of sc...
48
cards
10th March - Lymphoma/Leukaemia therapy
What is leukaemia,
What is lymphoma,
What is the main function of lymp...
23
cards
14th March - Future directions in therapeutics
What are the traditional forms of...,
Give an example of a cytotoxic dr...,
Which cytotoxic drug is on whos l...
19
cards
15th March- Future directions in cancer therapeutics II
What is induced essentiality,
How is protein quality control af...,
What is velcade
13
cards
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BS3003
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