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Abigail king
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Decks in this class (34)
Viruses
What does polyoma middle and larg...,
What do sv40 and adenovirus oncop...,
What are ltrs
10
cards
Metastasis
What increases in expression in i...,
What are the three mechanisms by ...,
What is n cadherin
10
cards
Angiogenesis
How are integrins involved in ang...,
What is the rip tag2 mouse model,
How are tumour vessels distinct f...
8
cards
Apoptosis
How was bcl 2 identified,
Outline the fas mediated pathway,
How does xiap function as an inhi...
10
cards
In Vitro transformation
What are the characteristics of v...,
Give examples of transformed cells,
Why do suspended cells have a red...
8
cards
Carcinogenesis
What is the main feature,
What two mechanisms allow metabol...,
How does carcinogen induced and v...
9
cards
Growth Factors
How does the processing of pdgf a...,
What growth factor is sis linked to,
How is egf discovered
9
cards
Gene Amplification
What are the main steps in illumi...,
What has the tcga project showed us,
What are the different types of d...
9
cards
Aetiology
How has incidence varied over the...,
What are the hormonal risk factor...,
What genetic factors contribute t...
9
cards
Growth Factor Receptors
How was egfr characterised,
How do we know that pdgf signalli...,
What is pertuzumab and how does i...
10
cards
Signalling Pathways
How is raf activated,
What is atf2 and what happens whe...,
What is a typical cascade involvi...
10
cards
PI3K
How can pisks become activated by...,
Pi3k lipids remain in the membran...,
How is mtorc1 affected by nutrien...
9
cards
Wnt, TGF-B, Hippo
What are the other roles of apc,
What are the b catenin target genes,
How is apc involved in the mitoti...
10
cards
Cell Cycle
What is the function of cdk1 and ...,
How do we know there are addition...,
What is cak and how does it lead ...
8
cards
Cell Cycle II
Which cyclins and cdks are essent...,
How did yeast studies help to ide...,
How was start explored in mammali...
12
cards
Tumour Suppressors
How do familial and sproadic form...,
How does rb act as a gatekeeper,
What are the preferences of prb p...
10
cards
Tumour Suppressors II
How do akt and chk1 2 phosphoryla...,
How is p21 involved in oncogenic ...,
What parts of the p53 pathway hav...
7
cards
Chromosomal Aberrations
Describe the philadelphia chromos...,
What are the second generation de...,
What is the function of myc
8
cards
Epidemiology
Name three advantages and disadva...,
What is advantageous in cohort st...,
Why are cohort studies sometimes ...
9
cards
Introduction
Outline the basic mechanism of ca...,
How do benign and malignant neopl...,
What is a carcinoma in situ
7
cards
Hedgehog
What happens to the hedghog pathw...,
Which glis are activator and whic...,
How are developmental outcomes co...
9
cards
Radiotherapy
What is the difference between io...,
How important are indirect effect...,
Why is oxygen beneficial in radio...
7
cards
Surgery
How is melanoma classified and wh...,
What kind of surgery is used for ...,
What is the effect of radiotherap...
7
cards
Tumour Immunology
What are the main differences bet...,
Outline the roles of th1 and th2,
What are coleys toxins
10
cards
Immune Therapy
There are many types of mab thera...,
What cancer type is rituximab use...,
Why do certain patients become re...
10
cards
Epigenetics
What does the epigenome aid under...,
What are the three main types of ...,
What makes up a solenoid
8
cards
Cancer Stem Cells
What are the requirements of canc...,
What proportion of cells can give...,
What is one limitation of an in v...
7
cards
miRNAs
What are micrornas,
How were multiple mir genes ident...,
Describe how short interfering rn...
7
cards
Gene Therapy
What are the advantages of a retr...,
What are the disadvantages associ...,
What are the main barriers to suc...
8
cards
Cancer Gene Therapy
Give two examples of suicide gene...,
Give one advantage and one disadv...,
What is an oncolytic virus
6
cards
DNA Repair
What intrinsic features of dna pr...,
What effect does cancer have on t...,
How does melanin confer protectio...
9
cards
RTKs
What about non rtks,
Why is imatinib so powerful and h...,
How does cetuximab inhibit egfr
9
cards
BRCA1/2
How does parp function,
What is lynparza,
Why is olympia
9
cards
Receptor Blockade
Give one example of each of the f...,
What are the functions of ctla 4,
What are the functions of pd 1
9
cards
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Cancer
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