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Pippa Griffiths
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Decks in this class (22)
lecture 1 - clearance
Define pharmacokinetics and its t...,
Define pharmacodynamics and its t...,
Parameters of pharmacokinetics 3
15
cards
lecture 2 - volume of distribution
Define the volume of distribution 1,
Name physiological determinants o...,
Describe why apparent volume of d...
10
cards
lecture 3 - absorption and half-life
Describe the extent of absorption 1,
Describe the rate of absorption 2,
Physiological determinants of ext...
10
cards
lecture 4 - drug metabolism
Importance of understanding biotr...,
Phase 1 of biotransformation 2,
Phase 2 of biotransformation 3
12
cards
lecture 5 - mechanisms of drug action
Describe 4 main sites of drug act...,
Describe affinity 2,
Define kd 3
11
cards
lecture 6 - drug targets
What is the only exception to pro...,
Process of neurotransmission 2,
Neurotransmitter synthesis 3
11
cards
lecture 7 - targets & RAAS
Role of raas 1,
What causes a release of renin 2,
Drugs targeting the raas 3
10
cards
lecture 8 - environment variability
What is the most important quanti...,
Body composition 2,
Renal function 3
12
cards
lecture 9 - genetic variability *
Pharmacogenomics pgx 1,
Pharmacogenetics pgt 2,
Predictable variability pharmacok...
7
cards
lecture 10 - drug interactions
What is a drug interaction 1,
Types of drug interactions 2,
Pharmacokinetic interaction 3
20
cards
lecture 11 - medicine regulations
Role of medsafe 1,
Products that medsafe regulates 2,
Products that medsafe doesn t reg...
14
cards
lecture 12 - drug development and clinical trials
Phases of drug development 1,
Define biomarker surrogate outcome 2,
Clinical trial design 3
8
cards
lecture 13 - poisons and poisoning
Diagnosis from pupils 1,
Diagnosis from skin 2,
Diagnosis from odour 3
12
cards
lecture 14 - pharmacodynamic principles and time course of immediate drug effects
Emax model 1,
Duration of response 2,
Emax model predictions 3
9
cards
lecture 15 - pharmacodynamic principles and time course of delayed drug effects
3 types of time courses for drug ...,
Mechanisms which explain delayed ...,
Explain why a drug effect may be ...
11
cards
lecture 16 - adverse drug reactions
Define an adverse drug reaction a...,
Allergy 2,
Side effect 3
13
cards
lecture 17 - target concentration intervention
Target concentration in clinical ...,
Why does pkpd vary 2,
3 ways to dose 3
10
cards
lecture 18 - clinical pharmacology and prescribing
Define rational prescribing 1,
Steps prior to writing a prescrip...,
In order to choose a medicine you...
11
cards
lecture 19 - principles of cancer therapy
Clinical presentation of cancer 1,
Diagnosis 2,
Cancer surgery 3
11
cards
lecture 20 - targeted cancer therapies
Cancer 1,
Pathophysiological basis of cancer 2,
Chemotherapy targeting cycling ce...
11
cards
random
What is the only drug that has a ...,
What are the physiological determ...,
Name 5 sites of drug actions on a...
15
cards
definitions
Clearance 1,
Volume of distribution 2,
Extend of absorption 3
34
cards
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CP
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