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Kathryn Chang
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Decks in this class (29)
Haemoglobin structure and function
Describe the structure of haemogl...,
Where does the polyphyrin ring bi...,
Hba
20
cards
Beta thalassemia
What happens in thalassemia,
Which haemoglobin is affected wit...,
What age does beta thalassemia ma...
24
cards
Sickle Cell Disease
What are the clinical features of...,
What is seen on the blood film of...,
What are the consequences of the ...
10
cards
Alpha thalassemia
How many alpha genes are there pe...,
Which chromosome are the alpha ge...,
What are the types of heterozygou...
14
cards
The Red Cell Membrane
What is the normal arrangement of...,
What molecules are important in t...,
What are the most significant rbc...
23
cards
The regulation of alpha globin- molecular mechanisms and therapeutics
What is the relationship between ...,
How does the structure of dna aff...,
Explain the control of globin cha...
3
cards
Haemoglobin E and C, Beta thalassemia and interactions
What is the pathophysiology of hbe,
What does hbe with bthal look like,
What does hbe homozygosity look l...
19
cards
Developmental haemopoiesis
Where is the first site of haemop...,
Where is the next site of gestation,
Where is the main site in normal ...
16
cards
Haemoglobinopathies in the Neonate
Where are embryonic haemoglobins ...,
Which are the fetal hbs,
Why is gower known as a transient hb
14
cards
Beta thalassemia intermedia
Why is there such heterogeneity f...,
What are the genotypes that can g...,
Explain how 2 thalassemic genes c...
11
cards
Antenatal screening
Outline how antenatal screening i...,
Outline how neonatal screening is...
2
cards
Indications and contraindications for transfusion in inherited red cell disorders
When is a sickle cell patient tra...,
What are the types of transfusion...,
What are the problems with exchan...
24
cards
Transfusion in developing countries
What are the challenges to transf...,
Who in low income countries uses ...,
What are the problems with recrui...
4
cards
Immunity and the red blood cell
What are the types of immunity,
What is the rh system,
What is the forward group and wha...
17
cards
haemolytic anaemia
What is the main cause of inherit...,
Describe the pathogenesis of here...,
Splenomegaly low hb low mcv retic...
9
cards
Extra Hb Structure and function
Explain how mutations in globin g...,
What kinds of mutation in the glo...,
What kinds of mutation in the glo...
5
cards
Enzymopathies
What enzymopathy is the most comm...,
Outline the clinical features of ...,
Describe the treatment for pyruva...
9
cards
Miscellaneous
HLH, PNH, Gene therapy, novel approaches to Hb-opathies
12
cards
The Spleen
Describe the histology of the spleen,
Describe the functional unit of t...,
Infectious causes of splenomegaly 3
9
cards
Iron Overload
What is the clinical definition o...,
What are the main causes of iron ...,
Outline the investigation and ass...
7
cards
Neonatal cases
What are the main causes of neona...,
Term baby with high jaundice on d...,
High jaundice and very mild anaem...
6
cards
Complement
Outline the activation of the cla...,
Outline the activation of the lec...,
Outline the activation of the alt...
6
cards
Bone Marrow Failure
6 month old baby presents with lo...,
8 year old child presents with an...,
Give 3 causes of acquired red cel...
10
cards
Random cases
Raised rdw mildly low hb blood fi...,
Low hb raised reticulocytes raise...,
Raised bilirubin raised alt low h...
7
cards
Molecular techniques in red cell disorders
What is the location of the beta ...,
What is the location of the alpha...,
What genes are involved in embryo...
20
cards
Malaria
Outline the lifecycle of malaria,
How does sickle cell anaemia prot...,
What host protein does p vivax re...
6
cards
Spleen
What is the spleen component of,
Describe the histology of the spl...,
How is the red pulp structured to...
12
cards
Red Cell Aplasia
What is pure red cell aplasia,
What can occur in rca which disti...,
What are the congenital causes of...
11
cards
Hereditary Haemochromatosis
Which transporters absorb iron wh...,
Which transporters export iron to...,
How is iron transporter how is it...
15
cards
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Haem - Module 3
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