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Rachael Adewole
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Decks in this class (16)
What cells are commonly involved in the generation of inflammation
What is an inflammatory response,
Acute inflammatory response,
Chronic inflammatory response
12
cards
Name the main effector components of the innate and the adaptive immune response
What is an immune response,
Define innate immunity and the co...,
Define adaptive immunity and the ...
5
cards
What are the main subtypes of T-cells
T cell subtypes,
Naive t cells,
Cytotoxic t cells
6
cards
Describe what is meant by antigen presentation
What is an antigen,
What does antigen presentation mean,
Presentation to what how where
3
cards
What are cytokines and explain the function of cytokines in health and disease
What are cytokines,
Interleukins,
Tumour necrosis factor tnf
5
cards
What is the difference between monoclonal and polyclonal antibodies
Monoclonal antibody function,
Monoclonal antibodies,
Polyclonal antibodies
6
cards
What are the main purposes of using indirect immunofluorescence in clinical immunology?
What is immunofluorescence and th...,
Importance of immunofluorescence,
Direct immunofluorescence
6
cards
What are the key differences between the tumour associated antigen and tumour specific antigen
What are antigens,
Tumour associated antigen taa,
Tumour specific antigen tsa
4
cards
Discuss the diagnostic values of thyroid transcription factor 1 (TTF-1) in lung adenocarcinoma
What type of antigen is ttf 1,
Detection method,
Diagnostic value
4
cards
Explain the major limitation of murine monoclonal antibody
Humanised antibody,
Limitation,
Alternative
5
cards
Provide a specific example of monoclonal antibody with bi-specific action
Monoclonal antibody,
Bi specific action,
Example of drug
6
cards
Describe the components and the mechanisms of action of these therapeutic agents in cancer
The main goal of antibody-drug conjugation as an anti-cancer agent is to release the cytotoxic drug to kill the tumour cell without harming the normal and healthy cells
4
cards
Explain the concept and process of chimeric antigen receptor development in immunotherapy
What is chimeric antigen receptor,
Mechanism of car t,
Challenges
5
cards
Discuss the limitation of chimeric antigen receptor therapy
Car t therapy,
Limited applicability,
Cytokine release syndrome crs
4
cards
Explain the immunomodulatory mechanism of tumor necrosis factor-beta (TNF-B) in multiple sclerosis
Multiple sclerosis is an autoimmune disease of the central nervous sytem (CNS) in which the CD4+ T cell of the T-helper 1 and 17 subset react against self myelin antigen
5
cards
Outline the principal mechanism by which tumour cells escape immune recognition
Down regulation of antigen presen...,
Loss of antigen,
Immune checkpoint activation
6
cards
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Immunology Questions
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