MSK/Skin

Compare and contrast the immune parameters of tuberculoid leprosy and lepromatous leprosy. Diagnose an infection with Nocardia. Identify the epidemiology and pathogenesis of plague, anthrax, and tularemia.

Compare and contrast the immune parameters of tuberculoid leprosy and lepromatous leprosy. Diagnose an infection with Nocardia.

Identify common microbial causes of pyoderma, impetigo, erysipelas, cellulitis, fasciitis, myositis, and osteomyelitis. Diagnose staphylococcal and streptococcal infection by microbiological lab results.

Be familiar with the clinical and histologic terms used to describe skin lesions Know the embryologic and morphologic characteristics of melanocytes Know the clinical and histologic presentation of nevocellular nevi and melanoma Know that other pigmented lesions and variants of melanocytic nevi exist Know the epidemiology of melanoma For melanoma, be familiar with the features that carry prognostic significance

Diagnose and treat superficial fungal skin infections. Differentiate black and white piedra. Identify ringworm infections. Diagnose and treat subcutaneous fungal skin infections.

Prescribe MMR vaccine for patients. Diagnose measles and mumps. Describe the pathogenesis of congenital rubella. Differentiate variola, vaccinia, and other pox viruses. Diagnose parvovirus infection.

Review pertinent H&P exam findings for non-inflammatory, inflammatory, reactive, and infectious joint pathology Discuss diagnostic work up of joint problems Review well known rheumatologic conditions Develop a differential diagnosis for joint pain

1. Describe the common bone related findings in genetic abnormalities of non-neoplastic bone lesions (Achondroplasia, osteogenesis imperfecta, osteopetrosis) 2. Describe the bone related findings and pathophysiology of common acquired structural abnormalities of non-neoplastic bone lesions (osteoporosis, Paget's disease, Osteomalacia, Hyperparathyroidism and renal osteodystrophy) 3. Describe the clinicopathologic features and common causes of osteonecrosis (avascular necrosis)

1. Describe the most common types of carcinoma that metastasize to the bone 2. Describe the clinicopathologic features of common benign neoplasms (osteochondroma, enchondroma, giant cell tumor) 3. Describe the clinicopathologic features of common malignant neoplasms (osteosarcoma, chondrosarcoma, Ewing sarcoma)

Be familiar with the clinical and histologic features of the acute inflammatory dermatoses:Urticaria, eczema/atopic dermatitis and erythema multiforme Be familiar with the clinical and histologic features of the acute inflammatory dermatoses:psoriasis, lichen planus and lupus erythematosus Be familiar with the clinical and histologic features of the autoimmune dermopathies: pemphigus vulgaris, bullous pemphigoid, dermatitis herpetiformis, and epidermolysis bullosa aquisita

Know the clinical and histologic features of seborrheic keratosis Know the clinical and histologic features of actinic keratosis Know the clinical and histologic features of squamous cell carcinoma Know the clinical and histologic features of basal cell carcinoma Know the clinical and histologic features of dermatofibroma Know the clinical and histologic features of dermatofibrosarcoma protuberans Know the clinical and histologic features of langerhans cell histiocytosis Know the clinical

Compare and contrast the epidemiology of infections caused by Brucella, Bartonella, Pasteurella, and Erysipelothrix. Identify the pathogenesis of infections caused by Brucella, Bartonella, Pasteurella, and Erysipelothrix.

1. Describe the limitations to the use of non-steroidal anti-inflammatory drugs in the treatment of rheumatoid arthritis. 2. Explain why the use of corticosteroids is controversial in the treatment of rheumatoid arthritis. 3. List the prototype “synthetic” disease modifying anti-rheumatic drugs, describe their mechanism of action and clinical uses, and list their major adverse effects. 4. List the prototype “biologic” disease modifying anti-rheumatic drugs, describe their mechanism of action

Be able to recall the inheritance pattern (AD/AR), genetic aberration, associated clinical findings and histology of cutaneous lesions in dysplastic nevus syndrome Be able to recall the inheritance pattern (AD/AR), genetic aberration, associated clinical findings and histology of cutaneous lesions in basal cell nevus syndrome (Gorlin syndrome) Be able to recall the inheritance pattern (AD/AR), genetic aberration, associated clinical findings and histology of cutaneous lesions in neurofibromato