This class was created by Brainscape user Meg Cunningham.

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Decks in this class (29)

L1 - The Pharmaceutical Industry
When was the emergence of the fir...,
What two industries did the 1st d...,
What drugs were first produced in...
32  cards
L2 - Drug discovery
What is intellectual property 1,
How does ip relate to pharmaceuti...,
4 types of ip 3
30  cards
L3 - Intro to oxidative stress
What is a free radical 1,
What is a common source of free r...,
Caged vs free radicals 3
33  cards
L4 - Oxidative damage to DNA
What are the main types of free r...,
Why is dna susceptible to free ra...,
Abasic site formation 3
29  cards
L5 - intro to protein oxidation
Why is it difficult to understand...,
What does direct protein damage i...,
What is the consequence of direct...
29  cards
L6 - Lipid oxidation
What is lipid peroxidation 1,
What is a polyunsaturated fatty a...,
Why are pufas prone to oxidation 3
24  cards
L7- antioxidants
Three broad strategies to protect...,
Define antioxidant 2,
4 criteria for an antioxidant 3
36  cards
L8 - Carbonyl trappers
Explain carbonyl stress 1,
An ideal carbonyl trapper 2,
Reproxalap 3
25  cards
L9 - biological biosensors
What is a biosensor 1,
What is the function of a biosens...,
Single shot biosensors vs long te...
41  cards
L10 - Organs-on-a-Chip
Why are different exposure patter...,
Describe the kind of animal speci...,
Long term studies 3
21  cards
L11- PHASE 1 (OXIDATIVE) PATHWAYS
Define drug metabolism 1,
3 naming systems used to describe...,
Old william s system phase 1 and 2 3
32  cards
L12 - PHASE 2 (CONJUGATIVE) PATHWAYS
Explain the basic features underl...,
Explain the rationale underlying ...,
Identify the 6 major cofactors in...
35  cards
L13 - INFLUX & EFFLUX DRUG TRANSPORTERS
Describe how transporters surmoun...,
Describe the distinctive features...,
Describe the distinctive features...
23  cards
L14- Xenosensors & CYP450 Induction
What is cyp450 induction 1,
9 factors that influence intervar...,
Hist ex1 cyp induction by barbitu...
34  cards
L15 - Drugs and the Gut microbiome
Describe the concept of the gut m...,
What regions of the gi tract are ...,
What 2 technologies used to map t...
20  cards
L16- Small Molecules vs Biologics
Describe biologics 1,
Describe biosimilars 2,
Describe biobetters 3
24  cards
L17- Clinical trials
Blank 1,
The phases of clinical drug trials 2,
The intention of each phase 3
9  cards
L18 - Clinical pharm 1
Key components of pharmacokinetics 1,
Key components of pharmacodynamics 2,
Define absorption 3
25  cards
L19 - clinical pharm 2
Define the therapeutic range 1,
Disintegration time 2,
Dissolution rate 3
23  cards
L20- Natural Products
List the 5 common chemical classe...,
Describe alkaloids 2,
Describe glycoside 3
25  cards
L21- Basic concepts of PGx
What are some factors that underl...,
Clinical example of clinical vari...,
Define phramacogenomics 3
29  cards
L22- CYP2D6
How many human pharmaceuticals do...,
What fraction of current drugs ar...,
Cyp2d6 prefers to metabolise what...
23  cards
L23- SLCO1B1
Identify the 2 major classes of t...,
Where are the major classes of tr...,
What transporter does the slco1b1...
26  cards
L24 - HLA Alleles
Toxicity vs adrs 1,
What is type a adr 2,
What is a type b adr 3
33  cards
L25 - DPYD and TPMT
Describe the origins of the idea ...,
What does dpyd stand for 2,
Describe the basic molecular biol...
35  cards
L26 - anxiolytics and hypnotics
What is the rationale for using a...,
What are the 6 main classes of an...,
Benzodiazepines _____ gaba a rece...
16  cards
L27 - Dementia
What two hallmark lesions identif...,
How do amyloid plaques and tau pr...,
Class of dementia 3
15  cards
L28- Cannabenoids and psychedelics
Describe the ecs system 1,
What are the components of the ec...,
The difference between endocannab...
25  cards
L29 - Photopharmacology
List the modalities of photopharm...,
Photopharmacology uses ____ to re...,
Principle of photopharmacology 3
16  cards

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PHAR3320

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