The Medicine Y3 Semester 1 - Drug disposition

This class was created by Brainscape user Grace Barnett. Visit their profile to learn more about the creator.

Decks in this class (14)

Introduction to absorption
What is pharmacokinetics,
What is pharmacodynamics,
What is absorption
13  cards
Drug absorption and bioavailability
What is bioavailability,
What is absolute bioavailability,
What is the relative bioavailability
12  cards
Drug absorption – part II and first-pass metabolism
Name the three times of route of ...,
Describe transcellular transport,
Transcellular transport dependent on
25  cards
Drug Distribution
Rate of distribution depends on,
Perfusion limited distribution,
When is perfusion limited distrib...
12  cards
Volume of distribution
Extent of distribution,
Volume of distribution,
Apparent volume that the drug occ...
20  cards
Tissue distribution
How is tissue binding measured,
Role of hepatic uptake and efflux...,
Importance of tissue distribution...
6  cards
Drug metabolism reactions
Xenobiotic,
Elimination is irreversible remov...,
Describe metabolism
17  cards
Clearance and hepatic elimination
What is elimination,
What is metabolism,
What is excretion
28  cards
Cytochrome p450
How many cyp genes,
Evolutionary changes in location,
Cyp membrane
27  cards
Conjugation Reactions
What are the phases of metabolism,
Phase ii reactions characteristics,
Resulting conjugates are extremel...
27  cards
Drug drug interactions
Types of drug drug interactions,
Relevance of drug drug interactions,
Modifiers of drug metabolism type...
21  cards
Transporter-mediated drug-drug interactions
Transporter mediated drug drug in...,
How many membrane transporters,
Two major super families of trans...
26  cards
Renal Elimination
Importance of renal excretion,
Changes in dosage regimen may be ...,
Structure of kidney
37  cards
Properties of metabolites
In most cases metabolites are _____,
Exceptions of inert metabolites,
How important are pharmacological...
21  cards

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The Medicine Y3 Semester 1 - Drug disposition

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