021815 path cervix

Question 1

uterine cervical lesions

Answer 1

cervicitis
neoplasia (most are by HPV)
non-HPV lesions (benign-polyps, cysts, leiomyoma. malignant-carcinomas, sarcomas)

Question 2

cause for cervical neoplasia

Answer 2

mainly HPV (oncogenic strains)

Question 3

risk factors for cervical neoplasia

Answer 3

early age at first intercourse
multiple sex partners
male partner with multiple previous sexual partners
persistent infec by high risk strains of HPV

Question 4

what does low risk HPV cause?

Answer 4

condyloma (in some)

Question 5

what differentiates LSIL from HSIL?

Answer 5

HSIL (CIN 2, 3) has higher nculear to cyto ratio

Question 6

does HPV vaccine replace need for cervical cancer screen?

Answer 6

no, b/c:
many at-risk women are already infected
the vaccine protects against only some of the HPV serotypes