#1

Question 0

Father of Immunology

Answer 0

Louis Pasteur

Question 1

Father of Immunology…Bacteriology & Germ Theory…Cell-Mediated Immunity…Humoral Immunity

Koch, Ehrlich, Pasteur, Metchnikov

Answer 1

Immunology - Pasteur
Bacteriology - Koch
Cell-Mediated - Metchnikov
Humoral - Ehrlich

Question 2

Father of Bacteriology

Answer 2

Robert Koch

Question 3

Father of Cell-Mediated Immunity

Answer 3

Metchnikov

Question 4

Father of Humoral Immunity

Answer 4

Paul Ehrlich

Question 5

Koch’s Postulates (4)
Pathogen:
1. …must be _______ in all cases
2. …can be ______ and ______ in pure culture
3. …_____ in pure culture must cause _______ in _____ ______
4. …must be re-_______ from new host and shown to be ______

Answer 5

1. must be present in all cases of disease
2. can be isolated and grown in pure culture
3. grown in pure culture must cause disease in healthy individual
4. reisolated from new host and shown to be same pathogen as original

Question 6

Gram Positive

Answer 6

Peptidoglycan

Question 7

Gram Negative

Answer 7

Lipopolysaccharide

Question 8

CIRCULATING Effector Cells (3)

1. ______phils
2. _________
3. __. __. ________

Answer 8

Neutrophils
Macrophages
NK Cells

Question 9

Circulating Effector PROTEINS (3)

1. You look nice today
2. _______-binding ______ (_______tin)
3. _-_______ _______ (Pentraxin)

Answer 9

Complement
Mannose-binding lecting (collectin)
C-Reactive Protein (pentraxin)

Question 10

Neutrophils produce (3)

1. gungnam style
2. too big to pee
3. luke skywalkers

Answer 10

Cytokines
Prostaglandins
Leukotrienes

Question 11

Neutrophil Granules Contain: (4)

1. H2O2-ase
2. Lies-o-mime
3. bad gradative Enz
4. D FE(ins)NSE

Answer 11

Peroxidase
Lysozymes
Degradative Enzymes
Defensins

Question 12

Eosinophil Granules 
Color?
Contain (3)
1.  Basic P
2. H2O2-ases
3. hand-soap substances

Answer 12

Red-pink

1. Basic Proteins
2. Peroxidases
3. Anti-microbial substances

Question 13

Mast Cells & Basophils
Color?
Contain:
(3)  &
(2)

Answer 13

Purple-black

1. Histamine 2. Serotonin 3. Heparin
2. Cytokines 2. Chemokines

Question 14

Macrophages are:
1  in CT:  his toe
2  in liver:  Cup 'fer
3  in lungs:  Alvy \_\_\_\_\_phages
4  in CNS:  micro\_\_\_\_\_\_ cells

Answer 14

CT - Histocytes
Liver - Kupffer cells
Lungs - Alveolar Macrophages
CNS - Microglial Cells

Question 15

Macrophages
produce and release _______ and __________ __________
(2 classes)

Answer 15

Enzymes

inflammatory mediators

Question 16

Macrophages
produce and release enzymes (2)
1. L
2. G

Answer 16

Lipase

Galactosidase

Question 17

Macrophages 
produce and release Inflammatory Mediators
(1) \_\_\_\_\_\_\_ & \_\_\_\_\_\_\_\_
(2) \_\_\_\_\_\_ \_\_\_\_\_\_ \_\_\_\_\_\_\_\_\_ (ROI)
(3) \_\_\_\_\_\_ \_\_\_\_\_\_ (NO)

Answer 17

Cytokines & Chemokines
Reactive Oxygen Intermediates (ROI)
Nitric Oxide (NO)

Question 18

NK Cells target: (3)

1. _____-infected cells
2. ______ cells (bronchoscopy)
3. _________ cells (buster’s hand)

Answer 18

1. Virus-infected cells
2. Cancer cells
3. Transplant cells

Question 19

NK Cells
Cytotoxic Mechanism
–> secretion of ______

Answer 19

Perforin

Question 20

PAMP

Answer 20

Pathogen-Associated Molecular Patterns

Question 21

PRR

______-tailed ______

Answer 21

Pattern Recognition Receptors

mannose-tailed glycans