1- Fixation

Question 1

Fixatives alter tissue by

Answer 1

Stabilizing the proteins so that it is resistant to further changes

Question 2

Fixatives change soluble contents of the cell into insoluble substances so:

Answer 2

Substances are not lost during the subsequent processing steps.

Question 3

When the protein molecule unfold and the internal bonds become disrupted is called

Answer 3

Denaturation

Question 4

Additive fixation process:

Answer 4

Disruption enables the protein to combine chemically with a fixative molecule, and the protein then becomes insoluble