When was ECT first used?
1938 - Bini and Cerletti
What is mortality rate of ECT?
1 in 50,000 (general anaesthetic)
What are some proposed mechanisms of action?
Effects on NA and serotonin receptors
Dopaminergic effects
When is ECT used?
Severe depression
Depression with psychosis
Catatonia
Manic episode
How is ECT administered?
Usually bilateral electrodes and just above seizure threshold
Use of general anaesthetic and muscles relaxant
2 times per week, 6-12 treatments
What are some side effects of ECT?
Amnesia Headache Muscles pain Confusion Nausea Nerve palsy
When is ECT contraindicated?
Cardiac conditions
Increased intracranial pressure
Pregnancy