10.2 Plasma complement regulators

Question 1

Dissociates C1r and C1s from C1q

Answer 1

C1 inhibitor (C1-INH)

Question 2

Cleaves C3b and C4b

Answer 2

Factor I

Question 3

Cofactor with I to inactivate C3b; prevents binding of B to C3b

Answer 3

Factor H

Question 4

Acts as a cofactor with I to Inactivate C4b

Answer 4

C4 binding protein (C4BP)

Question 5

Prevents attachment of the C5b67 complex to cell membrane

Answer 5

S protein (Vitronectin)