What are the three major fluid compartments in the body?
Total Body Water (TBW) Intracelular Fluid (ICF) Extracellular Fluid (ECF)
What is the approximate size of the ICF?
27L –> ~60% of TBW
What is the ionic composition of the ICF?
High: K+, Mg2+
Low: Na+, Cl-, Ca2+
What is the approximate size of the ECF?
18L –> 40% of TBW
What is the ionic composition of the ECF?
High: Na+, Cl-, Ca2+
Low: K+, Mg2+
What are the sub compartments of the ECF?
Plasma
Interstitial Fluid
Transcellular Fluid
How are fluid compartments volumes measured?
Put a known volume of indicator in
Extract a sample of compartment fluid to measure how it is diluted
Calculate the volume based on dilution