Where does resistance come from?
1) pre-existing genetic variation in the population
2) Gene flow
3) New mutations
How can herbicide resistance be stopped?
1) multi-herbicide treatment
2) rotation of different herbicides
Evolutionary rescue
the evolution of resistance in order to adapt and increase in abundance
Suppression gene drives
reduce the size of a population (potentially to extinction)
Replacement drives
amined to spread a human beneficial allele throughout a population
Single mutations
unlikely to confer resistance to multiple drugs with different mechanisms of action (lower viral loads make multiple mutations less likely)