13: Multiple Sclerosis

Question 1

Likely broad cause of MS

Answer 1

Childhood event or illness sensitizes immune system to attack myelin -> triggering event in adulthood

Question 2

Drugs for MS are mostly for what form?

Answer 2

Relapsing form

Question 3

Only MS drug approved for primary progressive form of MS

Answer 3

Ocrevus

Question 4

Two drugs used to treat acute MS exacerbations

Answer 4

1. High dose corticosteroids

2. ACTH (Acthar gel)

Question 5

What three autoimmune diseases are DDx for MS?

Answer 5

1. SLE with cerebri tis
2. CNS vasculitis
3. Polyarteritis Nodosa with transverse myelitis