18 Flashcards by Spring A

Q

Pain to cold:

A

Oxaliplatin

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Q

Oxaliplatin:

A

a platinum

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Q

Bavacizumab:

A

anti-angiogenesis

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Q

Cardiotoxic:

A

___-rubicin (anthracyclines= cytotoxic antibiotics)???

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Q

Vincristine MOA:

A

MOA: prevent formation of mitotic spindles

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Q

Taking Cyclosporine tell drs because:

A

can cause immunosuppression and
DDI’s

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Q

Can cause immunosuppression:

A

Methotrexate

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Q

Prednisone inhibits pain by blocking:

A

prostaglandin production

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Q

Can give if patient is on SSRIs (for HSV-1):

A

Acyclovir

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Q

Backbone drug for HIV:

A

NRTIs

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Q

HIV drug that works by inhibiting assembly:

A

Protease Inhibitors

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Q

HIV drug that causes INC in TG, etc:

A

Protease inhibitors

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Q

Prophylaxis Abx given when CD4<100:

A

Bactrim wasn’t an option, so I put
Azithro

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Q

Virus that isn’t life long:

A

influenza

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Q

Best for patient with xerostomia and mild candidiasis:

A

nystatin

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Q

Lowest potential for DDI;s:

A

nystatin

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Q

Azithromycinn Qweek

A

HIV

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Q

Azithromycin is only given once a day because:

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A

has longer t 1⁄2

Q

HIV treatment therapy:

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A

Genvoya

Q

Need ABx prophylaxis:

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A

artificial heart valve

Q

Influenza treatment:

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A

-“antidine”s or Tamiflu?

Q

Fluconazole MOA:

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A

prevent conversion of lanosterol into ergosterol

Q

Nystatin MOA:

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A

binds to ergosterol

Q

Interact with Warfarin:

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A

metronidazole, diflucan,????bactrim, cipro

EARLY odontogenic infections are primarly:

primarly: either + aerobes or – aerobes

Cluvandrate helps B-lactams against bacteria that produce:

B-lactamase

28. Main cause of endocarditis:

Strep

Active against + strep, -, and anerobes:

augmentin

Give for dental infection >3 days:

Clindamycin

Most likely to cause oral abscess:

bacteroides?

ADR of augmentin:

diarrhea

Want to give if patient is immunocompromised:

Amoxil (because it is CIDAL)

B-lactamase works by:

hydrolyzing penicillin

Best anerboic coverage:

metronidazole

36. Do not give cephalosporin if:

urticarial rash to pen

37. Not okay for preganancy:

doxy

Would need to add systemic abx:

fever

Cancer:

rapid proliferation and undifferenitation

Procedure that requires pre-med:

gingival manipulation

Chemo patients:

stomatitis will likely occur within 1 week

Can cause MRONJ:

not Tacrollimus

Kill HSV-1:

none

44. Block cell wall synthesis:

Pen (all B-lactams)

C.diff:

Clindaymcin