recall what makes up the cell membrane
a phospholipid bilayer where phospholipid’s hydrophobic tails come together to allow hydrophilic heads to face the outer & inner of the cell
while the phospholipid bilayer acts as a barrier to water soluble molecules & ions, what can easily cross
fat soluble molecules
small, non-polar molecules
hormones (hydrophobic)
what are the 4 different types of cell membrane proteins
transport
receptor
enzymes
anchoring
what are the 2 types of transport proteins in the membrane
channel & carrier proteins
channel proteins form a pore in the cell membrane to allow movement in/out of the cell, what type of transport is used
facilitated diffusion
recall how facilitated diffusion works, & the conditions
uses no energy as molecules just pass, but they must be non-polar & small
what common molecules are non-polar & small enough to easily pass the membrane
o2 & co2
carrier proteins bind to solutes to carry them across the membrane, what 2 types of transport use carrier proteins
facilitated diffusion & active transport
recall the difference between gated & non-gated channels
non-gated channels are always open but molecules move from high to low all the time, gated allows the channel to be open & closed
which transport protein is slower & more specific w/ molecules
carrier proteins are slower & more specific due to binding
GLUT transporters bind to glucose to carry it over the membrane, this is an example of a ____ protein
carrier protein
receptor proteins only bind to specific extracellular molecules called ____
ligands
an example of a receptor protein in the sarcolemma of skeletal muscle fibers are insulin receptors, what is the result of their presence
insulin will bind to the receptors, changing the membrane permeability to glucose which allows an increased uptake of glucose from the blood into the fiber
which proteins control the chemical reactions that take place on the outer face of the cell membrane
enzymes
acetylcholinesterase found on the outer surface of the sarcolemma of a muscle fiber is an example of which protein and functions to
enzymes! it cleaves & inactivates acetylcholine
recall the 3 functions of anchoring proteins in the membrane
recall & contrast the 3 types of junctions formed by anchor proteins
desmosomes - loose for flexibility
tight junctions - no movement
gap junctions - allow cytoplasmic connection like joint hotel rooms
the cell membrane contains carbohydrates, which can be located on glycoproteins/glycolipids. they are also located on the extracellular surface for what purpose
cell recognition aka identification
MHC I is a glycosylated protein in the plasma membrane of all nucleated cells in the body & is an example of a membrane carbohydrate, why is it not present in red blood cells
they don’t contain nuclei when they are mature – allowing blood to be donated from lack of identification
what membrane carbohydrate allows the immune system to distinguish self from non-self
MHC I
what are the 2 types of membrane transport
passive & active
passive transport refers to when solutes move from high to low concentrations, requiring no energy. the 3 examples of this transport are
simple diffusion
facilitated diffusion
carrier mediated
recall the difference between simple & facilitated diffusion
simple diffusion allows solutes to move across without proteins - o2 & co2
facilitated needs channel proteins for movement - na & k
what kind of molecules use carrier mediated transport
charged, polar, & large molecules