20. Agonists

Question 1

What is a ligand?

Answer 1

Chemical that specifically binds to a receptor

Question 2

What is an agonist?

Answer 2

Ligand that binds and causes a biological response

Question 3

What is the dose-response relationship?

Answer 3

Tissue response is generally directly proportional to the ratio of receptors occupied with the agonist

Question 4

What is potency?

Answer 4

Measure of drug activity

Question 5

What is a partial agonist?

Answer 5

One that never produces the max response

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Question 6

What does it mean to have spare receptors?

Answer 6

The maximum response has been reached but not all receptors used

Question 7

Name two ways of studying drug interactions

Answer 7

1. Functional studies

2. Binding studies