2009

Question 0

Osteomalacia Dg & lab results

Answer 0

Decreased mineralization of the newly formed osteoid at sites of bone turnover; can be caused by:

• nutritional (malabsorption, gastric bypass, celiac)
• t2RTA, primary renal phosphate wastingin CKD
• chr liver d
• direct inhibition of bone mineralization
• labs: low Ca & PO4, low urine Ca, high PTH, low Vit D, high ALP

Question 1

ABPA Tx

Answer 1

Prednisone +/- itraconazole, if require significant doses of steroids

Question 2

Asthma control assessment

Answer 2

Good control:

- daytime sy 80% predicted or personal best

Question 3

Co poisoning, fist line Tx and indications for hyperbaric O2:

Answer 3

• 100% O2
• hyperbaric, if:
  1. CarboxyHb >25% or >20% if pregnant
  2. LOC
  3. Ph<7.1
  4. End-organ damage (ECG changes, C/P)

Question 4

AAA - Sx and f/u recommendations

Answer 4

ACC/AHA 2005

• Sx repair > 5.5 cm
• 4-5.4 cm: U/S or CT q6-12/12
• 3-4 cm: U/S or CT q2-3 yr

Question 5

Gold Tx complications (for RA)

Answer 5

Low Plt, agranulocytosis, pancytopenia

Question 6

RA heme complications

Answer 6

An of chr d, Fe-deficient, megalopolis tic anemia, rarely AIHA (DAT +)

Question 7

Evans sy

Answer 7

Cytopenias, AIHA (DAT+ warm agglutinins) w low Plt - in kids w SLE

Question 8

Adult onset Still’s d - yamaguchi criteria

Answer 8

• Fever >39 x >1 wk
• Salmon colour maculopapular rash
• arthralgias/arthritis >2 wk
• leu >10
  Minors:
• pharyngitis
• lymphadenopathy
• abn LEs
• HSM
• neg ANA/RF

2 major and 3 minor
Usually high ferritin

Question 9

HyperTG

Answer 9

Eruptive xanthoma
HSM
Pancreatitis, abdo pain
Memory loss

Question 10

Hypercholesterolemia

Answer 10

Xanthelasma

Tendon xanthoma

Question 11

Oral hairy leukoplakia

Answer 11

EBV - can be in HIV, ass w intense EBV replication

Question 12

Sensitivity (true positives)

Answer 12

=TP/TP+FN

Question 13

Specificity (true negatives)

Answer 13

=TN/TN+FP