1
Q
Apalutamide
A
Strong inducer, Substrate
2
Q
Aprepitant
A
Inducer, Moderate inhibitor, Substrate
3
Q
Armodafinil
A
Inducer
4
Q
Bosentan
A
Moderate inducer, Substrate
5
Q
Brigatinib
A
Inducer, Substrate
6
Q
Carbamazepine
A
Strong inducer, Substrate
7
Q
Corticosteroids
A
Inducer
8
Q
Dabrafenib
A
Inducer, Substrate
9
Q
Efavirenz
A
Moderate inducer
10
Q
Encorafenib
A
Strong inducer
11
Q
Enzalutamide
A
Strong inducer, Substrate
12
Q
Etravirine
A
Moderate inducer, Substrate
13
Q
Lorlatinib
A
Moderate inducer, Substrate
14
Q
Lumacaftor
A
Moderate inducer
15
Q
Modafinil
A
Moderate inducer
16
Q
Nevirapine
A
Inducer, Substrate
17
Q
Phenobarbital
A
Inducer
18
Q
Phenytoin
A
Strong inducer
19
Q
Rifabutin
A
Inducer, Substrate
20
Q
Rifampicin
A
Strong inducer
21
Q
Ritonivir
A
Inducer, Strong inhibitor, Substrate
22
Q
Rufinamide
A
inducer
23
Q
St John’s wort
A
strong inducer
24
Q
Vemurafenib
A
inducer, Substrate
25
Amiodarone
Inhibitor, Substrate
26
Asciminib
Inhibitor, Substrate
27
Atazanavir
Moderate inhibitor, Substrate
28
Avacopan
Inhibitor, Substrate
29
Ceritinib
Strong inhibitor, Substrate
30
Ciclosporin
Moderate inhibitor, Substrate
31
Clarithromycin
Strong inhibitor, Substrate
32
Cobicistat
Strong inhibitor, Substrate
33
Crizotinib
Moderate inhibitor, Substrate
34
Darunavir
Inhibitor, Substrate
35
Diltiazem
Moderate inhibitor, Substrate
36
Encorafenib
Inhibitor, Substrate
37
Erythromycin
Moderate inhibitor, Substrate
38
Fluconazole
Moderate inhibitor
39
Fluvoxamine
Moderate inhibitor
40
Grapefruit juice
Moderate inhibitor
41
Idelalisib
Strong inhibitor, Substrate
42
Imatinib
Moderate inhibitor, Substrate
43
Isavucinazole
Moderate inhibitor, Substrate
44
Itraconazole
Strong inhibitor, Substrate
45
Ketoconazole
Strong inhibitor, Substrate
46
Larotrectinib
Inhibitor, Substrate
47
Lenacapavir
Moderate inhibitor, Substrate
48
Letermovir
Moderate inhibitor
49
Lopinavir
Inhibitor, Substrate
50
Maribavir
Inhibitor, Substrate
51
Miconazole
Inhibitor
52
Netupitant
Inhibitor, Substrate
53
Palbociclib
Inhibitor, Substrate
54
Posaconazole
Strong inhibitor
55
Ribociclib
Inhibitor, Substrate
56
Stiripentol
Inhibitor, Substrate
57
Ticagrelor
Inhibitor, Substrate
58
Verapamil
Moderate inhibitor, Substrate
59
Voriconazole
Strong inhibitor, Substrate
60
Abemaciclib
Substrate
61
Abiraterone
Substrate
62
Acalabrutinib
Substrate
63
Alfentanil
Substrate
64
Alprazolam
Substrate
65
Amitriptyline
Substrate
66
Apixaban
Substrate
67
Apremilast
Substrate
68
Aripiprazole
Substrate
69
Atorvastatin
Substrate
70
Avacopan
Substrate
71
Avanafil
Substrate
72
Avatrombopag
Substrate
73
Axitinib
Substrate
74
Betamethasone
Substrate
75
Bictegravir
Substrate
76
Bortezomib
Substrate
77
Brentuximab vedotin
Substrate
78
Brexpiprazole
Substrate
79
Buspirone
Substrate
80
Budesonide
Substrate
81
Busulfan
Substrate
82
Cabazitaxel
Substrate
83
Cabozantinib
Substrate
84
Cannabidol
Substrate
84
Cariprazine
Substrate
85
Cinacalcet
Substrate
86
Cisapride
Substrate
87
Clopidogrel
Substrate
88
Cobimetinib
Substrate
89
Cocaine
Substrate
90
Codeine
Substrate
91
Colchicine
Substrate
92
Cyclophosphamide
Substrate
93
Dapoxetine
Substrate
94
Darifenacin
Substrate
95
Darolutamide
Substrate
96
Dasatinib
Substrate
97
Dexamethasone
Substrate
98
Diazepam
Substrate
99
Disopyramide
Substrate
100
Docetaxel
Substrate
101
Domperidone
Substrate
102
Donepezil
Substrate
103
Eletriptan
Substrate
104
Elexacaftor
Substrate
105
Elvitegravir
Substrate
106
Enfortumab vedotin
Substrate
107
Entrectinib
Substrate
108
Eplerenone
Substrate
109
Ergometrine
Substrate
110
Erlotinib
Substrate
111
Esomeprazole
Substrate
112
Ethinylestradiol
Substrate
113
Etonogestrel
Substrate
114
Etoposide
Substrate
115
Etoricoxib
Substrate
116
Everolimuse
Substrate
117
Felodipine
Substrate
118
Fentanyl
Substrate
119
Finerenone
Substrate
120
Fluticasone
Substrate
121
Fluvastatin
Substrate
122
Fostemsavir
Substrate
123
Galantamine
Substrate
124
Gefitinib
Substrate
125
Filteritinib
Substrate
126
Guanfacine
Substrate
127
Haloperidol
Substrate
128
Hydrocortisone
Substrate
129
Ibrutinib
Substrate
130
Ifosfamide
Substrate
131
Imipramine
Substrate
132
Irinotecan
Substrate
133
Ivabradine
Substrate
134
Ivacaftor
Substrate
135
Lapatinib
Substrate
136
Lemborexant
Substrate
137
Lercanidipine
Substrate
138
Levonorgestrel
Substrate
139
Lidocaine
Substrate
140
Lurasidone
Substrate
141
Macitentan
Substrate
142
Maraviroc
Substrate
143
Mavacamten
Substrate
144
Methylprednisolone
Substrate
145
Midazolam
Substrate
146
Midostaurin
Substrate
147
Mifepristone
Substrate
148
Mirabegron
Substrate
149
Mirtazipine
Substrate
150
Nifedipine
Substrate
151
Nilotinib
Substrate
152
Nimodipine
Substrate
153
Nirmatrelvir
Substrate
154
Norethisterone
Substrate
155
Olaparib
Substrate
156
Omeprazole
Substrate
157
Ondansetron
Substrate
158
Osimertinib
Substrate
159
Oxycodone
Substrate
160
Paclitaxel
Substrate
161
Perampanel
Substrate
162
Pazopanib
Substrate
163
Pomalidomide
Substrate
164
Ponatinib
Substrate
165
Propranolol
Substrate
166
Quetiapine
Substrate
167
Quinine
Substrate
168
Reboxetine
Substrate
169
Regorafenib
Substrate
170
Rilpivirine
Substrate
171
Ripretinib
Substrate
172
Risperidone
Substrate
173
Rivaroxaban
Substrate
174
Romidepsin
Substrate
175
Ruxolitinib
Substrate
176
Salmeterol
Substrate
177
Sildenafil
Substrate
178
Silodosin
Substrate
179
Simvastatin
Substrate
180
Siponimod
Substrate
181
Sirolimus
Substrate
182
Solifenacin
Substrate
183
Sonidegib
Substrate
184
Sorafenib
Substrate
185
Sunitinib
Substrate
186
Suvorexant
Substrate
187
Tacrolimus
Substrate
188
Tadalafil
Substrate
189
Tamoxifen
Substrate
190
Tezacaftor
Substrate
191
Tiagabine
Substrate
192
Tofacitinib
Substrate
193
Tolterodine
Substrate
194
Tolvaptan
Substrate
195
Toremifene
Substrate
196
Trabectedin
Substrate
197
Tramadol
Substrate
198
Triamcinolone
Substrate
199
Ulipristal
Substrate
200
Upadacitinib
Substrate
201
Vandetanib
Substrate
202
Velpatasvir
Substrate
203
Venetoclax
Substrate
204
Venlafaxine
Substrate
205
Vinblastine
Substrate
206
Vincristine
Substrate
207
Vinorelbine
Substrate
208
Voxilaprevir
Substrate
209
Warfain (R-isomer)
Substrate
210
Zanubrutinib
Substrate
211
Ziprasidone
Substrate
212
Zolpdem
Substrate
