phase 0 of cardiac AP
upstroke, Na+ intracellular shift
phase 1 cardiac AP
early fast repolarization, Ca2+ intracellular/K+ extracellular shift
phase 2 cardiac AP
plateau, K+ extracellular shift
phase 3 cardiac AP
repolarization to diastolic potential, K+ extracellular shift
phase 4 cardiac AP
resting membrane potential
absolute refractory preiod
no stimulus, no matter how strong, can initiate a new AP
relative refractory period
a stronger than normal stimulus can initiate a new AP
supranormal period
small stimuli which normally wouldn’t trigger depolarization can initiate a new AP
SA node
pacemaker of heart, located in RA, initiate electrical impulse
atrial conduction pathway
impulse spread through atrial muscle, causes atrial contraction
AV node
located in junction between atria and ventricles, delays the impulse to allow ventricles to fill
bundle of his
conducts impulse from AV node to ventricles
right and left bundle branches
carry impulses down the interventricular septum
purkinje fibers
throughout ventricular walls, trigger ventricular contraction
what does the ecg machine detect?
electrical changes in heart muscle resulting from depolarization and repolarization
describe each ecg wave
P wave: depolarization of atria in response to SA node triggering
PR interval: delay of AV node to allow ventricles to fill
QRS complex: depolarization of ventricles
ST segment: beginning of ventricular repolarization
T wave: ventricular repolarization
ECG measurement: each small box is ____, 5 small boxes is _____, 10 small boxes is _____
1mm, 5mm, 1 cm
how many 1mm boxes in 1 sec at the 25 mm/sec? how many in 1 sec at 50 mm/sec?
25, 50
how to calculate HR at paper speed 25 mm/s
count R waves in 3 sec (15 boxes) x 20
OR count R waves in 6 sec (30 boxes) x 10
how to calculate HR at paper speed of 50 mm/s
count number of R waves in a 6 sec strip (60 large squares) and x 10 to get BPM OR count # of R waves in 30 sec (30 boxes) and x 20
how to calculate instantaneous HR
50 mm/sec: count # of boxes between R waves and divide by 3000
25 mm/sec: count # of boxes between R waves and divide by 1500
normal dog ECG values and rhythms
HR: 60-160 bpm in adults, up to 180 bpm for toy breeds, up to 220 bpm for puppies
normal rhythm: sinus rhythm, sinus arrhythmia, wandering SA pacemaker
normal cat ECG values
HR: 160-240 bpm
cardiac rhythms: normal sinus rhythm, sinus tachy
basic ECG interpretation
determine predominant rhythm, analyze complexes, determine mean electrical axis, identify arrhythmias