When do peripheral nerve fibers reach their maximum diameter?
2 to 5 years
when is myelination of peripheral nerve fibers complete?
age 5 years
motor conduction velocities - when do they reach adult values?
ages 3-5 years
when do CMAP amplitudes reach adult values
end of first decade of life
what happens to f-waves in children?
no changes in f-wave latency as the arm length and conduction velocity are increasing a lot from age 0 to 3 years, but after age 3, arm length continues to increase and the F wave latency increases commensurately now that myelination is more stable
h-reflexes in kids
you can get lots of H reflexes in many nerves up to age 1 because of the lack of myelination, then it is difficult to obtain. In adults, you can usually only get tibial to soleus and radial nerve to FCR
in newborns, what is considered abnormal repetitive nerve stimulation?
decrement of 10% or more between initial and fourth or fifth responses at 2 Hz, or an increment of greater than 23% at 20-50 Hz
EMG MUAP durations in infants
1-4msec (in adults, it’s 3-15msec)
electrodiagnostics findings in CMT
depends if demyelinating or axonal form.
demyelinating form has MNCV <38 and axonal form has MNCV >38 in median nerve
CMT1 - needle EMG shows defibrillation with sharps, large polyphasic MUAPs.
CMT2 - chronic denervation and reinervations
type 1 diabetes and electrodiagnostic findings
impaired motor distal latency and SNAP amplitude
infantile botulism electrodiagnostic findings?
normal motor and sensory nerve conductions. RNS abnormal
needle EMG with small MUAPs and sometimes sharps and fibs