What are the 3 stages of labour?
What happens in the 1st stage of labour?
Creation of birth canal:
When diameter does the birth canal need to be expanded to in the Creation of the Birth Canal
10cm
What triggers Cervix Ripening?
Prostaglandins
What happens in Cervix Ripening?
What happens in the 2nd stage of labour?
Expulsion of foetus
What happens in the 3rd stage of labour?
Expulsion of placenta and changes to minimise blood loss from mother
What are the properties of uterine smooth muscle cells that facilitate labour?
Myometrium
How does contraction but only PARTIAL relaxation of the myometrium fibres help in labour?
This shortens fibres and pushes foetus from the top
What are the properties of uterine contractions in EARLY pregnancy?
What are the properties of uterine contractions in LATE pregnancy?
What are Braxton-Hicks contractions?
High amplitude contractions every now and then
BUT not strong enough to move foetus into labour
What are the roles of uterine contractions? (2 things)
What hormone makes contractions more frequent?
Oxytocin
Increases APs by lowering the threshold
What hormone makes contractions more forceful?
Prostaglandins
Increases Ca2+ per AP
What hormone softens the cervix?
Prostaglandins
Where are prostagandins produced?
Endometrium
What oestrogen : progesterone ratio causes an increase in prostaglandin secretion?
Oestrogen > Progesterone
Oestrogen is prostaglandins friend
Progesterone isn’t because they’re both P’s and he’s salty
What does a reduction in progesterone do?
Increases prostanglandin release which in turn:
Where is oxytocin secreted from?
Posterior pituitary (controlled by hypothalamus)
What increases oxytocin release?
Afferent impulse from cervix and vagina (postive feedback)
What does oxytocin act on?
Smooth muscle receptors:
Increases amount of receptors if oestrogen > progesterone
Basically oxytocin increases sensitivity
What hormone promotes labour?
Prostaglandins
How is labour artificialy induced with Prostaglandins? (2 things)
Vaginal gel