9. Catecholamines

Question 1

types of Catecholamines

Answer 1

Norepinephrine
Epinephrine
Isoprenaline
Dopamine

Question 2

Norepinephrine

Answer 2

α > β1 >>> β2 
short DOA 
for shocks (not anaphylactic) 
↑ MAP ↑Sys ↑Dia ↑PP 
causes reflex bradycardia

Question 3

Epinephrine

Answer 3

β1 = β2 > α 
short DOA 
Bronchodilation 
for anaphylactic shock 
no dramatic change in MAP LD: ↓Dia HD: ↑Sis => ↑PP 
given w/ local anesthetics

Question 4

Isoprenaline

Answer 4

β1 = β2
Bronchodilation
for bradycardia and heart block
↓ MAP ↓Dia

Question 5

Dopamine

Answer 5

D > β > α
LD: D1 ,MD: β1 & HD: no selectivity => +α
LD: increase renal blood flow; MD: +tive inotropic effect
for cardiogenic shock
bad pharmacokinetics