What is it
Dysfunction of the abducens nerve (cranial nerve VI), which controls the lateral rectus muscle, leading to impaired outward eye movement (abduction).
Clinical Features
Horizontal diplopia (double vision, worse when looking to the affected side) ππ
Inability to move the eye outward (lateral gaze palsy) β‘οΈ
Eye remains turned inward (esotropia) at rest ποΈβ©οΈ
Head turn to the affected side to compensate πΎβοΈ
Epidemiology
Most common isolated cranial nerve palsy
Often due to microvascular disease or raised intracranial pressure (ICP)
Can be congenital or acquired
Age Groups Affected
Children: More likely due to congenital causes or increased ICP (e.g., hydrocephalus)
Adults (>50 years): More likely due to vascular causes (diabetes, hypertension)
Any age: Trauma, tumors, or infections
Risk Factors
β
Modifiable:
Diabetes mellitus π¬
Hypertension
Obesity & atherosclerosis
Smoking π¬
Head trauma π
π« Non-Modifiable:
Increased ICP (e.g., tumors, hydrocephalus, meningitis, idiopathic intracranial hypertension)
Brainstem stroke
Congenital CN VI palsy
Clinical Presentation
πΉ Microvascular CN VI Palsy (Common in Diabetes, Hypertension):
Painless
Improves over weeks to months
πΉ Raised ICP-Related CN VI Palsy (Emergency π¨):
Bilateral CN VI palsy
Headache, nausea, vomiting π€’
Papilledema (swelling of optic disc on fundoscopy)
πΉ Trauma or Tumor-Related CN VI Palsy:
Gradual onset if tumor-related
Other cranial nerve palsies may be present
Prognosis
πΉ Depends on the cause:
Microvascular disease: Usually recovers in 3β6 months
Trauma-related: Variable recovery, may need surgery
Tumor or ICP-related: Requires urgent intervention
πΉ Prevention: Control diabetes, hypertension, and weight; seek early medical care for head trauma or ICP signs π¨
Test
H - test
Outcomes - medial gaze = inability to look laterally