Abx Classifications

Question 1

Do PCNs cover MRSA

Answer 1

No

Question 2

What are the 1st generation cephalosporins that cover mostly gram + (staph and strep) not MRSA

Answer 2

cephalexin (Keflex)

cefazolin (Ancef)

Question 3

2nd gen cephalosporins are more gram - coverage and are used more for what

Answer 3

respiratory infections

Question 4

3rd gen cephalosporin examples? coverage?

Answer 4

• ceftriaxone (Rocephin)
• Ceftibuten (cedax)
• cefoxatime (Claforan)
• less gram pos, more gram neg

Question 5

___ is a 4th generation cephalosporin and has pseudomonal activity with good gram ____ coverage

Answer 5

• cefepime (Maxipime)

- gram positive

Question 6

which is the only cephalosporin to have MRSA coverage

Answer 6

ceftaroline (Teflaro)

Question 7

Carbapenems are part of the _____ family and have gram ____ coverage

Answer 7

• beta-lactam

- negative

Question 8

_____ are watched carefully due to high risk of resistance

Answer 8

Carbapenems

Question 9

Ertapenem has ____ coverage but NO pseudomonas coverage

Answer 9

negative

Question 10

what are the beta-lactam inhibitors? which has pseudo coverage?

Answer 10

• amoxicillin/clavulanic acid (Augmentin)
• piperacillin/tazobactam (Zosyn) = Psuedo Cov.
• ampicillin/sulbactam (Unasyn) (dog/cat bites)

Question 11

which bacteria do fluoroquinolones cover

Answer 11

gram - and gram +

cipro and levofloxacin have good pseudo coverage

Question 12

what are the fluoroquinolones? which are good for resp?

Answer 12

• ciprofloxacin
• levofloxacin (resp)
• moxifloxacin (resp)

Question 13

what do macrolides cover

Answer 13

• atypical pna
• pertussis
• H. flu
• some gram +

Question 14

what are ex of macrolides

Answer 14

• erythromycin
• azithromycin
• clarithromycin

Question 15

what do sulfas cover? example?

Answer 15

gram - and MRSA

trimethoprim/sulfamethoxazole (Bactrim)

Question 16

lincosamide ex? what does it cover

Answer 16

• clindamycin

- gram + and anaerobic (ABOVE diaphragm)

Question 17

glycopeptide ex? what does it cover

Answer 17

vancomycin

gram + and MRSA

Question 18

differentiate between vancomycin routes of administration

Answer 18

PO = for c. diff
IV = systemic

Question 19

tetracycline examples? what do they cover

Answer 19

• doxycycline
• minocycline
• tetracycline

gram + and MRSA
skin and some respiratory

Question 20

Glycylcyline ex? what does it cover?

Answer 20

tigecyline (Tigacyl)

BROAD, w/ MRSA,
NO pseudo

Question 21

Oxazolidinones ex? what does it cover

Answer 21

-zolids

gram + and MRSA

Question 22

Lipopeptide ex? coverage?

Answer 22

daptomycin (Cubicin)

gram + and MRSA
no lung penetration

Question 23

Nitroimidazole ex? coverage?

Answer 23

• metronidazole (Flagyl)
• tinidazole (Tindamax)

anaerobic coverage BELOW diaphragm

Question 24

commons antifungals and typical coverage

Answer 24

• fluconazole (Diflucan) – general yeast
• miconazole (Monistat) – vag yeast
• voriconazole (Vfend) – serious fungal infxn, molds