Acid Base/Buffering

Question 1

What is normal blood pH?

Answer 1

7.35 - 7.45

Question 2

Why can hemoglobin act as a buffer?

Answer 2

Because Histidine side chains can take up or release protons

Question 3

What are the key buffers of the blood in the body?

Answer 3

Phosphate, hemoglobin, and carbonic acid/bicarbonate

Question 4

What controls the majority of pH changes or lack of in the blood?

Answer 4

Bicarbonate buffering

Question 5

What causes diabetic ketoacidosis?

more common in type one

Answer 5

Lots of keytone bodies are produced from acetyl-CoA.

H+ are released during the production of ketones resulting in metabolic acidosis.