Acne

Question 0

Acne Tx

Answer 0

• Topical retinoid (adaptelene gel) or systemic retinoid
• Topical or oral Abx
• Benzoyl peroxide

“Do not apply topic retinoids and benzoyl peroxide at the same time as benzoyl peroxide oxidizes retinoids. Alternating days if use both.”
2-3 months to see effect.

Question 1

Acne pathogenesis

Answer 1

"Clogged pores"   = comedome
     Pores = pilosebaceous unit
Inflammation
Infection
   Bacteria- Propionibacterium acnes and granulosum

Question 2

Acne Rosacea

Answer 2

Middle aged
No comedome
Flushing 
Facial nasal labia area
Papules and pustules superimposed on a background of Telangiectasias and general erythema
Rhinophyma - enlarged nose

Question 3

Benzoyl peroxide

Answer 3

• bA topic Meds with both antibacterial and comedolytic properties
• Both Prescription and OTC
• adverse effects
  
  • bleaching of hair, colored fabric, or carpet
  • may irritate skin; discontinue of severe

Question 4

Topical or oral Abx

Answer 4

Tetracycline
Doxycycline
Minocycline

It takes 2-3 months to see improvement

Question 5

Oral isotretinoin

Answer 5

• For severe, nodulocystic acne failing other therapies
• 5-6 months course
• Teratogenic
  
  • female must be enrolled in FDA-mandated prescribing program in order to use this Meds
  • two forms of contraception must be used during the therapy and for one month after tx has ended

Question 6

isotretinoin

Answer 6

Common side effects:

• Xerosis (dry skin)
• Cheilitis (chapped lips)
• Elevated liver enzymes
• Hypertiglyceridia

Question 7

Open comedome

Answer 7

“Blackhead”

Question 8

Closed comedome

Answer 8

“Whitehead”

Question 9

Acne

Answer 9

“Pimples”

Question 10

Acne Vulgaris

1. Presence of hormones (androgens)
2. Sebaceous gland activity
3. Plugging of the hair follicle
4. P. Acnes (Bacteria) in the hair follicles

Answer 10

Pathogenesis

Question 11

Oral isotretinoin

Answer 11

Teratogenic

Question 12

Spironolactone

Answer 12

Has anti-androgenic effects

Question 13

Acne Rosacea

Answer 13

The absence of comedies helps to distinguish acne vulgaris from Rosacea

Question 14

Acne

Answer 14

Adolescent

Question 15

Acne

Answer 15

Predisposing factors

• XXY chromosomal phenotype
• Polycystic ovarian syndrome
• Hyperandrogenism
• Hypercortisolism
• Precocious puberty