occurs when
iris bulges forward and seals off trabecular meshwork
where does pressure particularly build up
posterior chamber, causing pressure behind the iris worsening the closure angle
risk factors
age female FHx chinese + east asian origin shallow anterior chamber
medications which can precipitate closed angle glaucoma
adrenergic meds: noradrenalin
anticholinergic medications
tricyclic antidepressants e.g. amitriptyline
presentation
unwell acute onset -severely painful red eye -blurred vision -halos around lights -assoc headache, nausea, vomit
OE
red eye teary hazy cornea decreased visual acuity fixed + dilated pupil firm eyeball on palpation
initial Mx
pilocarpine
acts on muscarinic receptors to cause constriction of pupil –> miotic agent
open up flow for aqueous humour
acetazolamide
carbonic anydrase inhibitor
reduced production aqueous humour
2ry care - medication option
pilocarpine acetazolamide hyperosmotics - glycerol, mannitol timolol dorzolamide brimonidine - sympathomimetic
definitive Mx
laser iridotomy