What are the levels of usbstacne cuse disorder?
mild
moderate
severe
What is substance use disorder?
problematic use of substance
What is mild substance use disorder?
“abuse”
ability to self-regulate
generally non-catastrophic harm
lower levels of salience
What is mod/severe substance use disorder?
addiction
what is biological process of reward?
changes of brain tissues
What are behavioral diagnosis?
misuse
abuse
addiction
What is psudeo-addiction?
pain condition that was under treated –> tx it? –> give pt analgesic –> STOP addiction behaviors
What drugs can causes dependency?
alcohol benzo opiates ssri snri
What neurotransmitter gives reward to the brain?
dopamine
What is the ventral tegmental area –> nucleus acumbens?
“warm fuzzy”
very old part of the brain
“imprints” of memories
What does addiction mean?
compulsive use despite harm
What does salience mean?
stressed –> lean towards the ‘good’ imprints in the brain
Salience in tx?
ask: do you miss being high or under the influence?
emotional loading about this issue
Drinking?
men 4/day
women 3/day
likely to lead to mild to mod degree of physical dependence in many patients
Alcohol?
dopamine reward –> euphoric buzz
changes in the GABA system of the brain
deep physical dependency –> potentially fatal withdrawal
Alcohol tx?
abstinence is difficult –> “just drink less”
Alcohol withdraw - prognosis?
untreated –> DEATH
Alcohol raving reduction?
naltrexone/vivitrol acamprosatee/campril topamax varenciline/chantix CBT
Stimulants?
PROFOUND dopamine release
Cannabis?
two main components: THC (intoxicating), CBD (nonintoxicating)
euphorigenic effects from dopamine release
influences HR, appetite, level of consciousness/awareness/cognition
withdrawal sx –> physical dependency
Cannabis - YA use for 12 mo?
mental health disorders 20 yrs later
Cannabis - heavy use in teen yrs?
8-10 pt IQ reduction
Opioids?
pain pills to heroin
cx: abscess, heart valve, brain fxn
Narcan?
opioid antagonist