Addison Disease and Steroid Hormones
Insufficient Cortisol and Aldosterone
Cause of Addison
Autoimmune
Surgical removal of adrenal glands
Sudden stop of adrenocortical hormone therapy
S&S of Addison (7)
Bronze pigmentation Changes in body hair (women's mustache)? Hypoglycemia Hypotension Weight loss Weakness Dehydration
Labs and Addison
Low Na
Low blood glucose
High K+
High WBC
Management Addisons
Hormonal Replacement: Hydrocortisone (Solu-Cortef) or mineralocorticoid (fludrocorticose)
Cushing and Steroid Hormones
Increase of Cortisol
Causes of Cushing
Use of corticosteroid meds
Tumor of pituitary gland
S&S Cushing
HTN Fat pads (Buffalo) Thin extremities Poor wound healing Moon face Obesity Abdominal striae Amenorrhea Hair growth Hyperglycemia
Labs for Cushing
High Na
High blood glucose
Low K+
Medical management Cushing
Taper corticosteroids Decrease risk of injury/infection Encourage ret Moderate activity Promote skin intergrity