Additional

Question 1

how does 3tc resistance occur

Answer 1

methionine turns into valine at RT184

Question 2

what does 3tc(lamuvidine) resistance drugs occur to?

Answer 2

Emtricitidine
abacavir
lamiduvine

(They arent exaclt resistamt, but more so complement eachothers mechanisms, when 3tc gets resistace)

Question 3

what is abacavir alleles?

Answer 3

HLA-B5701 - indian Americans

Question 4

what is carbamazepine alleles?

Answer 4

HLA-A3101 jap/caucasian
HLA-B1502 Chinese

Question 5

what enzyme is used in opioid metabolism?

Answer 5

CYP2D6

Question 6

what enzyme is used in warfarin metabolism?

Answer 6

CYP2C9
VKORC1

Question 7

what is maraviroc?

Answer 7

anti-CCR5

Question 8

what is brentixumab

Answer 8

binds to CD30
for NHL