What are treatment line for ADHD for severe and persistent symptoms?
lisdexamfetamine or methylphenidate
Dexamfetamine (unlicensed) if beneficial response to lisdex but cannot tolerate longer duration of action.
atomexitine
How long should each option be tried for before switching to alternative?
6 weeks
How should patients be monitored for the effectiveness and side effects?
sleep pattern
sexual dysfunction (atomexitine)
stimulant diversion
misuse
what are alternatives and why are they not used?
Bupropion
modafinil
venlafaxine
Lack of evidence- not recommended without specialist advice