ADHD - Segars

Question 1

Function of STIMULANTS for ADHD

Answer 1

Enhance NE/DA/5-HT transmission via interfering with pre-synaptic reuptake by VMAT –> increased NT release

Question 2

Stimulant drugs for ADHD

Answer 2

Amphetamine
Dextroamphetamine
Lisdexamphetamine
Methamphetamine
Methylphenidate
Dexmethylphenidate

Question 3

**ADHD Stimulant drugs - FDA regulations?

Answer 3

• 1 month supply
• No refills
• No samples

Question 4

Side effects of amphetamine stimulants for ADHD

Answer 4

• Decreased appetite
• Insomnia
• HA, abdominal pain
• Irritability, aggression
• Elevated BP/HR – stroke, MI

Question 5

Non-stimulant meds for ADHD

Answer 5

• Atomoxetine
• Guanfacine
• Clonidine

Question 6

Function of NON-stimulants for ADHD

Answer 6

Enhance NT transmission via inhibiting re-uptake (Atomoxetine) of NE or activating CNS alpha-2 receptors (Guanfacine, Clonidine)

Question 7

**Onset of activity for stimulants vs. non-stimulants

**Who is given the non-stimulant drugs for ADHD?

**Regulations on non-stimulant drugs for ADHD?

Answer 7

Stimulants = 24 hours
Non = 2-4 weeks

Intolerance to stimulants or parent resistance to stimulants

NONE (not controlled)

Question 8

Can non-stimulants be broken up and put in/on food?

Answer 8

NO

Question 9

Different side effects of non-stimulants compared to stimulants?

Answer 9

• HYPOtension
• Dizziness
• Sedation/somnolence

Question 10

Adderall

• Form?
• Drug(s)?
• Age?
• Percentage of each? (XR)

Answer 10

Pill

d,l-amphetamine, dextroamphetamine

3+

XR = 50/50

Question 11

Dexedrine

• Form?
• Drug(s)?
• Age?

Answer 11

Spansules (capsule that releases drug over time)

Dextroamphetamine

3+

Question 12

Vyvanse

• Form?
• Drug(s)?
• Age?

Answer 12

Pill

Lisdexamfetamine (pro-drug of dextroamphetamine)

6+

Question 13

Concerta

• Form?
• Drug(s)?
• IR or DR?
• Percentage of each? (XR)
• Age?

Answer 13

Pill

d,l-methylphenidate

BOTH (2 phases)

22% immediate (outer coat), 78% delayed

6+

Question 14

Ritalin

• Form?
• Drug?
• IR or DR?
• Percentage of each? (XR)
• Age?

Answer 14

Pill

d,l-methylphenidate

BOTH

50/50

6+

Question 15

Metadate

• Form?
• Drug(s)?
• IR or XR?
• Percentage of each? (XR)
• Age?

Answer 15

Pill

d,l-methylphenidate

BOTH

30/70

6+

Question 16

Aptensio

• Form?
• Drug(s)?
• IR or XR?
• Percentage of each? (XR)
• Age?

Answer 16

Pill

d,l-methylphenidate

BOTH

40/60

6+

Question 17

Daytrana

• Form?
• Drug(s)?
• Location? For how long?
• Onset?
• Age?

Answer 17

**PATCH

d,l, methylphenidate

Hip - 9 hours (for 12 hours of action)

1-2 hours

6+

Question 18

Quillivant

• Form?
• Drug(s)?
• IR or XR?
• Percentage of each? (XR)
• Age?

Answer 18

Extended-release ORAL SUSPENSION (powder)

d-methylphenidate

BOTH

20/80

6+

Question 19

QuilliChew - how is it different than Quillivant?

Answer 19

Extended-release CHEWABLE TABLET

Question 20

Focalin

• Form?
• Drug(s)?
• IR or XR?
• Percentage of each?
• Age?

Answer 20

Pill

Dexmethylphenidate

BOTH

50/50

6+

Question 21

Approved age for non-stimulant drugs?

Answer 21

6+