ADPKD

Question 1

Ultrasonic criteria for diagnosis

Answer 1

Age 15-39 need 3 or more cysts (uni or bilaterally)
40-59 need two in each
69+ need 3 or more in each

Question 2

Extra-renal manifestations

Answer 2

Hypertension (excess renin production)
Polycythaemia (excess EPO production)
Berry aneurysms
Liver cysts (hepatomegaly)
Cardiac valve disease (mitral prolapse most common)
Diverticula disease
Aortic aneurysm

Question 3

Cause if abdominal pain in ADPKD

Answer 3

Infected cyst

Bleeding into cyst

(Also diverticula disease, nephrolithiasis, hernia conplication, ruptured AAA, tuberous sclerosis complex