Adrenaline

Question 1

Adrenaline - mode of action

Answer 1

Naturally occurring alpha and beta adrenergic stimulant
BETA 1 - increases HR by increasing SA firing rate, increases conduction velocity through AV node, increases myocardial contractility, increases irritability of ventricles
BETA 2 - bronchodilation
ALPHA - peripheral vasodilation

Question 2

Adrenaline - indications

Answer 2

1. Cardiac arrest
2. Shock
3. Bradycardia with poor perfusion
4. Anaphylaxis
5. Severe asthma
6. Croup

Question 3

Adrenaline - contraindications.

Answer 3

1. Hypovolaemic shock without adequate fluid replacement

Question 4

Adrenaline - precautions

Answer 4

1.Consider lower doses for:
- elderly/ frail
- Pts with cardiovascular disease
- pts on MAOI

2. Higher doses may be required for Pts on Beta Blockers

Question 5

Adrenaline - side effects

Answer 5

1. Tachycardia
2. Supraventicular arrhythmias
3. Ventricular arrhythmias
4. Hypertension
5. Pupillary dilation
6. May increase size of MI
7. Feeling of anxiety/palpitations