Ageing Process

Question 1

list cellular factors contributing to ageing

Answer 1

mutations in chromosomes and mitochondria
intracellular and extracellular aggregates
cellular loss
cellular senescence
extracellular protein cross links

Question 2

what are telomeres and what happens to them during ageing

Answer 2

tips of chromosome, shorten throughout life due to cell division
leading to cell senescence

Question 3

describe frailty

Answer 3

increased vulnerability to decompensation after a stressor event
loss of homeostasis and resilience

Question 4

describe multimorbidity

Answer 4

having more than one chronic health condition increases risk of adverse events, poorer quality of life and hospital admission