1
Q
Statin + grapefruit juice
A
- BAD!!!
2
Q
Metronidazole + alcohol -
A
BAD!!!
3
Q
Warfarin + cranberry
A
- bad
4
Q
Warfarin+ amiodarone -
A
amiodarone potentiate anticoagulant effect
5
Q
Statin + clarithromycin
A
- BAD!pl
6
Q
Calcium + thyroxine
A
- decreased absorption from GIT
7
Q
Warfarin + NSAID
A
- BLEED (but not with low dose aspirin)
8
Q
ACEi + Spironolactone
A
- hyperkalaemia
9
Q
Digoxin + verapamil
A
- digoxin toxicity
10
Q
Fluoxetine + phenelzine
A
- serotonin syndrome (hyperthermia, tremor and cardiovascular 6??)
11
Q
B1 deficiency -
A
Wernicke’s encephalopathy (usually due to alcohol abuse) - ophthalmoplegia, ataxia and confusion (can lead to irreversible Korsakoff’s syndrome- confabulation) Tx: Pabrinex
12
Q
Delirium - fluctuating mental state + inattention + disorganised thinking and/or altered level of consciousness (1+2 + either 3 or 4 or both)
A
13
Q
Triptans contraindicated in IHD, uncontrolled hypertension, concurrent use of lithium, SSRI or ergot derivative drugs (such as cabergoline in PD)
A
