AJVR 2

Question 1

A domestic rabbit was challenged with RHDV2 following vaccination. Which of the following best describes the outcome in vaccinated animals?
A. All vaccinated rabbits developed clinical signs.
B. Most vaccinated rabbits showed mild illness.
C. None of the vaccinated rabbits exhibited clinical disease or mortality.

Answer 1

C. None of the vaccinated rabbits exhibited clinical disease or mortality.

Question 2

A study tested SC administration of opioids in ferrets. What was concluded about hydromorphone at 0.2 mg/kg?
A. It provided no antinociceptive effect.
B. It significantly increased withdrawal latencies.
C. It caused severe sedation without pain relief.

Answer 2

B. It significantly increased withdrawal latencies.

Question 3

What was found regarding the use of a vessel-sealing device (VSD) on the cervical-vestibular junction (CVJ) in rabbits?
A. VSD was superior to ligatures in sealing CVJ.
B. VSD created seals at the CVJ that were often ineffective.
C. VSD achieved consistent high-pressure seals at the CVJ.

Answer 3

B. VSD created seals at the CVJ that were often ineffective.

Question 4

In a pharmacokinetic study of CBD and CBDA in rabbits, what effect did feeding have on oral bioavailability?
A. Feeding increased CBD and CBDA plasma concentrations.
B. Feeding had no effect on cannabinoid absorption.
C. Feeding decreased the oral bioavailability of CBD and CBDA.

Answer 4

C. Feeding decreased the oral bioavailability of CBD and CBDA.

Question 5

How did plasma lactulose-to-mannitol ratios compare to urine ratios for assessing intestinal permeability in pigs?
A. Plasma ratios were not correlated with urine ratios.
B. Plasma ratios could be used to substitute urine ratios.
C. Only urine ratios were valid for permeability assessment.

Answer 5

B. Plasma ratios could be used to substitute urine ratios.

Question 6

What was the main finding regarding hydromorphone pharmacokinetics in guinea pigs?
A. IV and IM administration showed poor bioavailability.
B. IM administration had high bioavailability and longer mean residence time.
C. The drug was ineffective via either route.

Answer 6

B. IM administration had high bioavailability and longer mean residence time.

Question 7

In a study comparing laparoscopic and open ovariectomy in rabbits, what was the result?
A. Laparoscopic surgery reduced pain and recovery time.
B. Both techniques showed similar postoperative outcomes.
C. Open surgery caused significantly more complications.

Answer 7

B. Both techniques showed similar postoperative outcomes.

Question 8

In guinea pigs undergoing pneumoperitoneum, what was concluded regarding gastrointestinal effects?
A. CO2 insufflation caused severe postoperative ileus.
B. Pneumoperitoneum resulted in measurable stress markers only.
C. CO2 insufflation did not cause undue pain or stress.

Answer 8

C. CO2 insufflation did not cause undue pain or stress.

Question 9

Which intra-abdominal pressure (IAP) was considered acceptable for creating laparoscopic working space in guinea pigs?
A. 2 mm Hg
B. 4 mm Hg
C. 6 mm Hg

Answer 9

C. 6 mm Hg

Question 10

Which analgesic protocol provided deeper anesthesia in black-tailed prairie dogs?
A. Alfaxalone-ketamine-midazolam (AKM)
B. Alfaxalone-ketamine-dexmedetomidine (AKD)
C. Both AKM and AKD produced a deep plane of anesthesia

Answer 10

C. Both AKM and AKD produced a deep plane of anesthesia

Question 11

What was observed about laryngotracheal dimensions in rabbits regarding ETT placement?
A. The narrowest part is at the tracheal bifurcation.
B. The caudal thyroid cartilage is the limiting site.
C. Dimensions are constant along the airway.

Answer 11

B. The caudal thyroid cartilage is the limiting site.

Question 12

How did the rabbit model perform in testing a classical swine fever virus subunit vaccine?
A. The model was unreliable due to variable response.
B. Rabbits showed consistent antibody response and protection.
C. Only high-dose vaccines produced a response.

Answer 12

B. Rabbits showed consistent antibody response and protection.

Question 13

What was the conclusion about cold atmospheric plasma sterilization (CAPS) for implants?
A. CAPS caused more tissue inflammation than steam sterilization.
B. CAPS was noninferior to steam sterilization.
C. CAPS was ineffective in bacterial elimination.

Answer 13

B. CAPS was noninferior to steam sterilization.

Question 14

Which rodent species were the main reservoirs in HFRS outbreaks in Hubei, China?
A. Mus musculus and Microtus fortis
B. Rattus norvegicus and Apodemus agrarius
C. Meriones unguiculatus and Peromyscus maniculatus

Answer 14

B. Rattus norvegicus and Apodemus agrarius

Question 15

What technique was described for central venous catheterization in pigs?
A. Surgical cutdown of the jugular vein
B. Percutaneous insertion using the Seldinger technique under ultrasound
C. Direct venous puncture without imaging

Answer 15

B. Percutaneous insertion using the Seldinger technique under ultrasound

Question 16

In rabbits, what error occurs with glucometer readings at extreme PCV values?
A. Low PCV causes falsely high glucose readings.
B. High PCV causes falsely low glucose readings.
C. Both high and low PCV distort readings; correction formulas help only for HPBG.

Answer 16

C. Both high and low PCV distort readings; correction formulas help only for HPBG.

Question 17

What effect did mavacoxib have in rabbits at 6 mg/kg?
A. It failed to reach therapeutic concentrations.
B. It maintained target levels in all rabbits for >48 hours.
C. It reached target levels in 50% of rabbits for 48 hours.

Answer 17

C. It reached target levels in 50% of rabbits for 48 hours.

Question 18

How effective was TPUD compared to PACTD for measuring cardiac output in pigs?
A. TPUD significantly overestimated cardiac output.
B. TPUD showed acceptable agreement with PACTD.
C. TPUD measurements were not usable.

Answer 18

B. TPUD showed acceptable agreement with PACTD.

Question 19

What was found about NP volume measurement methods in rabbits?
A. MRI and gross methods were more accurate than water volumetry.
B. Water volumetry was the most accurate standard.
C. NP volume was constant across disk levels.

Answer 19

B. Water volumetry was the most accurate standard.

Question 20

Which variable best predicted correct endotracheal tube (ETT) size in rabbits?
A. Breed
B. Body weight
C. Skull width

Answer 20

B. Body weight