Alkylating agents Flashcards by Elizabeth Mertens

Q

MOA

A

Cause DNA cross-linking–>prevent replication

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Q

Intrinsic resistance

A

p53 mutation

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Q

Nitrogen mustards

A

Cyclophosphamide

Melphalan

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Q

Nitrosureas

A

Carmustine, lomustine

Streptozotocin/Streptozocin

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Q

Hydrazines

A

Procarbazine

Dacarbazine

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Q

Platinums

A

Cisplatin

Carboplatin

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