What is the peak age for ALL?
2-5yo
What genetics are associated with a good prognosis in ALL?
del(9p)
What genetics are associated with a poor prognosis in ALL?
Philadelphia chromosome t(9;22)
What are some good prognostic indicators in ALL?
pre B phenotype
Low initial WCC
FAB l1 type
What are some poor prognostic indicators in ALL?
FAB L3 type
T or B cell surface markers
Philadelphia translocation
MAle
CNS involvement
Initial WCC >100