1
Q
How does an allergen cause a release of mediators of inflammation?
A
Allergen causes IgE synthesis
IgE attached to mast cell surface
Cross linking of IgE by allergen allowing calcium ions entry
Mast cell degranulation and release of mediators
2
Q
What are the clinical features of allergic rhinitis?
A
Nasal itching
Rhinorrhoea
Sneezing
Conjunctival symptoms
3
Q
Do antihistamines penetrate the BBB and have muscarnic side effects?
A
Yes to both
4
Q
How do decongestants work?
A
A- adrenoceptor agonists cause vasoconstriction
Reduce flow mucus
Act locally
5
Q
What is urticaria caused by?
A
Release of histamine
AAI
flashcards
Decks in class (24)
# Cards
-
Immunology & Allergy11
-
Lung Fuction and Structure7
-
Smooth Muscle6
-
Histamine Chemistry3
-
Steroids, Leukotrienes And Muscarinic Antagonists8
-
Respiratory Pharmacology13
-
Allergy5
-
Pharmaceutics (aerosols)19
-
Adrenaline Chemistry5
-
Delivery Systems And Formulation For Inhalation12
-
Manufacturing Of Sterile Pharmaceutical Products10
-
Drug Delivery To The Eye3
-
Nasal Drug Delivery5
-
Supply of Medicines From Hospital5
-
Diagnosis & Treatment Of Asthma And COPD10
-
QSAR2
-
Law: Wholesale Supply5
-
Law: MURS & NMS5
-
Arthiritis14
-
Inflammatory Bowel Disease6
-
Food Allergy & Food Intolerance10
-
Food Allergy & Food Intolerance10
-
Health Economics10
-
Topical Drug Delivery And to the ear18
