Amyloid

Question 1

Describe the hyaline appearance of amyloid?

Answer 1

amorphous, glasys, and cartilage-like properties

Question 2

CNS Degenerative Diseases caused by PrPsc (new prion protein conformations)

Answer 2

Kuru
Creutzfeldt-Jakob Disease
Gerstmann-Straussler-Sheinker Disease
Scrapie
Bovine Spongiform Encephalopathy (Mad Cow Disease)

Question 3

What chromosome is the AB gene on?

Answer 3

21 (associated with Down syndrome)

Question 4

Amyloid deposited in the islets of Langerhans in T2D is derived from what precursor?

Answer 4

a Peptide related to a variant of calcitonin termed islet amyloid polypeptide or amylin.