Anemia

Question 1

Hemoglobinopathies

Answer 1

inherited disorders that affect structure, function and production of hemoglobin
eg: sickle cell disease
Thalassemia

Question 2

Patient at risk for hemoglobin electrophoresis

Answer 2

African
Mediterranean
Middle Eastern
southeast Asian
West Indian descent
or
If low MCV/MCH

Question 3

Hemoglobinopathies

Answer 3

AA hemoglobin = Normal hemoglobin
AS hemoglobin = sickle cell trait (heterozygous)
SS hemoglobin = sickle cell disease (homozygous)

AA hemoglobin in conjunction with a microcytic RBC and normal ferritin level suggests: Alpha Thalassemia

Decreased levels of HbA1, Increased levels of HbA2 and hemoglobin F = beta thalassemia